Discovery of a highly potent CECR2 bromodomain inhibitor with 7H-pyrrolo[2,3-d] pyrimidine scaffold.
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DOI: 10.1016/j.bioorg.2022.105768
Abstract: Cat eye syndrome chromosome region candidate 2 (CECR2) bromodomain is a module of CECR2-containing remodeling factor (CERF), which is a chromatin remodeling complex correlating with transcriptional control and adjustment of chromatin architecture. Potent chemical probes… read more here.
Keywords: pyrimidine scaffold; cecr2 brd; pyrrolo pyrimidine; cecr2 bromodomain ... See more keywords