Structure‐toxicity relationship of cefoperazone and its impurities to developing zebrafish by transcriptome and Raman analysis
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2017.04.025
Abstract: ABSTRACT Cefoperazone (CFP) is a potent antibacterial agent that is widely used for the treatment of bacterial infections. Previously, we found that both the C‐7 and C‐3 substituents of CFP are toxic functional groups, and… read more here.
Keywords: cefoperazone; analysis; structure toxicity; cfp ... See more keywords
PP-49 Population pharmacokinetics and dosing optimisation of cefoperazone in children
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2017-esdppp.94
Abstract: Background Cefoperazone is used in children with sus-pected or documented Gram-negative serious infections. Currently, its use is off-label partly because of lack of phar-macokinetic studies. Our aim was to evaluate the pop-ulation pharmacokinetics of Cefoperazone… read more here.
Keywords: cefoperazone; cefoperazone children; population pharmacokinetics; pharmacokinetics dosing ... See more keywords
Effects of Tigecycline combined with Cefoperazone on bacterial clearance and serum biochemical indexes in patients with pulmonary infections in ICU
Sign Up to like & getrecommendations! Published in 2022 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.38.6.5872
Abstract: Objectives: To investigate the effects of tigecycline combined with Cefoperazone on bacterial clearance and the expression of serum biochemical indexes [C-reactive protein (CRP), leukocyte count (WBC) and procalcitonin (PCT)] in patients with infection in an… read more here.
Keywords: cefoperazone; group; serum biochemical; treatment ... See more keywords
Case Report: Drug-Induced Immune Haemolytic Anaemia Caused by Cefoperazone-Tazobactam/ Sulbactam Combination Therapy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2021.697192
Abstract: There has previously been a report of a patient developing haemolytic anaemia following exposure to cefoperazone. Another case has been reported involving the detection of cefoperazone-dependent antibodies in the absence of immune haemolytic anaemia. To… read more here.
Keywords: cefoperazone; tazobactam sulbactam; report; haemolytic anaemia ... See more keywords