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In vivo translational assessment of the GES genotype on the killing profile of ceftazidime, ceftazidime/avibactam and meropenem against Pseudomonas aeruginosa

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Published in 2022 at "Journal of Antimicrobial Chemotherapy"

DOI: 10.1093/jac/dkac232

Abstract: Abstract Objectives To evaluate the in vivo killing profile of human-simulated exposures of ceftazidime, ceftazidime/avibactam and meropenem against GES-harbouring Pseudomonas aeruginosa in the murine thigh infection model. Methods Five P. aeruginosa isolates [three isogenic (GES-1,… read more here.

Keywords: ceftazidime; ceftazidime ceftazidime; avibactam meropenem; ceftazidime avibactam ... See more keywords