Ceftriaxone induces glial EAAT‐2 promotor region via NF‐kB conformational changes: An interaction analysis using HADDOCK
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30370
Abstract: Excitotoxicity, depletion of energy metabolites, and ionic imbalance are the major factors involved in neurodegeneration mediated through excitatory amino acid transporter‐2 (EAAT‐2) dysfunction in ischemic insult. Recent studies have revealed that ceftriaxone expresses EAAT‐2 via… read more here.
Keywords: interaction; dna; energy; conformational changes ... See more keywords
Population pharmacokinetics and dose optimization of ceftriaxone for children with community-acquired pneumonia
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Clinical Pharmacology"
DOI: 10.1007/s00228-020-02939-4
Abstract: To assess ceftriaxone population pharmacokinetics in a large pediatric population and describe the proper dose for establishing an optimized antibiotic regimen. From pediatric patients using ceftriaxone, blood samples were obtained and the concentration was measured… read more here.
Keywords: community acquired; population pharmacokinetics; ceftriaxone; population ... See more keywords
Antibiotic prophylaxis and surgical site infections; a prospective open label study to clinically evaluate the serum and tissue concentration of single dose prophylactic ceftriaxone in laparoscopic cholecystectomy
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Clinical Pharmacology"
DOI: 10.1007/s00228-020-02940-x
Abstract: Objective The goal of administering preoperative systemic prophylactic antibiotics is to have the concentration in the tissues at its optimum level at the start and throughout the surgery. The rationale for the use of antibiotics… read more here.
Keywords: laparoscopic cholecystectomy; tissue; tissue concentration; serum tissue ... See more keywords
Ceftriaxone dosing in patients admitted from the emergency department with sepsis.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of clinical pharmacology"
DOI: 10.1007/s00228-020-03001-z
Abstract: PURPOSE Unbound ceftriaxone pharmacokinetics in adult patients have been poorly characterised. The objective of this study is to determine the ceftriaxone dose that achieves an unbound trough concentration ≥ 0.5 mg/L in > 90% of… read more here.
Keywords: sepsis; emergency department; department sepsis; ceftriaxone ... See more keywords
Carbon Dots Green Synthesis for Ultra-Trace Determination of Ceftriaxone Using Response Surface Methodology
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Fluorescence"
DOI: 10.1007/s10895-019-02400-5
Abstract: The present study sought to develop a facile and green synthetic approach for producing fluorescent carbon dots (CDs) from a natural biomass using aqueous extraction of carbonized blue crab shell. Spherical carbon dots (6.00 ± 3.0 nm) exhibited… read more here.
Keywords: ceftriaxone; methodology; carbon dots; response surface ... See more keywords
Ceftriaxone Attenuated Anxiety-Like Behavior and Enhanced Brain Glutamate Transport in Zebrafish Subjected to Alcohol Withdrawal
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemical Research"
DOI: 10.1007/s11064-020-03008-z
Abstract: Chronic and/or excessive consumption of alcohol followed by reduced consumption or abstention can result in Alcohol Withdrawal Syndrome. A number of behavioral changes and neurological damage result from ethanol (EtOH) withdrawal. Ceftriaxone (Cef) modulates the… read more here.
Keywords: zebrafish subjected; etoh withdrawal; withdrawal; ceftriaxone ... See more keywords
Cellulose acetate/SiO2-poly(2-Acrylamido-2-methylpropane sulfonic acid) hybrid nanofiltration membrane: application in removal of ceftriaxone sodium
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-018-1470-4
Abstract: AbstractRemoval of ceftriaxone sodium antibiotic from water using cellulose acetate (CA) mixed matrix nanofiltration membranes was investigated in this work. Silica nanoparticles were functionalized with (3-aminopropyl)triethoxysilane (APTES). Then, the hydrophilic and negatively charged 2-acrylamido-2-methyl-1-propanesulfonic acid… read more here.
Keywords: ceftriaxone; ceftriaxone sodium; cellulose acetate; nanofiltration ... See more keywords
Cephalosporin antibiotics are weak blockers of GABAa receptor-mediated synaptic transmission in rat brain slices.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.04.008
Abstract: Cephalosporins are beta-lactam antibiotics that are extensively used in medical practice and are reported to cause epileptic seizures in some patients. The primary cause of cephalosporin-induced convulsions is believed to be their ability to block… read more here.
Keywords: brain slices; ceftriaxone; gabaa receptor; synaptic transmission ... See more keywords
Synthesis of pH responsive, photocrosslinked gelatin-based hydrogel system for control release of ceftriaxone.
Sign Up to like & getrecommendations! Published in 2021 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2021.105101
Abstract: Stimuli-responsive or smart nanocarriers are emerging class of materials used for drug delivery and tissue engineering applications. The objective of this study was to develop environment friendly, economic and smart gelatin based hydrogel for controlled… read more here.
Keywords: based hydrogel; hydrogel system; drug; gelatin based ... See more keywords
Ceftriaxone pharmacokinetics by new simple and sensitive ultra-high-performance liquid chromatography method.
Sign Up to like & getrecommendations! Published in 2017 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2017.02.012
Abstract: Ceftriaxone is a cephalosporin antibiotic with a potent antimicrobial activity and excellent penetration in most body fluids such as pleural, peritoneal, spinal and brain. These facts contribute to the application of ceftriaxone in the treatment… read more here.
Keywords: chromatography; peritoneal fluid; method; plasma peritoneal ... See more keywords
Evaluation of Tenckhoff Catheter Use and Ceftriaxone Intraperitoneal Administration in Horses
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Equine Veterinary Science"
DOI: 10.1016/j.jevs.2017.01.011
Abstract: &NA; Peritonitis in horses persists with high incidence and mortality, requiring more innovative and effective therapeutic strategies. The aim of this study was to evaluate Tenckhoff catheters and intraperitoneal use of ceftriaxone in horses. Ten… read more here.
Keywords: use ceftriaxone; ceftriaxone; administration; tenckhoff catheter ... See more keywords