Combinatorial InVitroFlow-assisted Mutagenesis (CombIMut) yields a 41-fold improved CelA2 cellulase.
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DOI: 10.1002/bit.28110
Abstract: The combination of diversity generation methods and ultrahigh-throughput screening (uHTS) technologies is key to efficiently explore nature's sequence space and elucidate structure-function relationships of enzymes. Beneficial substitutions often cluster in a few regions and simultaneous… read more here.
Keywords: invitroflow assisted; cela2 cellulase; cela2; mutagenesis ... See more keywords