Cytotoxic abietane and kaurane diterpenoids from Celastrus orbiculatus
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DOI: 10.1007/s11418-019-01326-3
Abstract: Celastrus orbiculatus is a medicinal plant belonging to the Celastraceae family. In this survey on the secondary metabolites of plants for obtaining antitumor substances, the chemical constituents of the stems of C. orbiculatus were investigated.… read more here.
Keywords: celastrus orbiculatus; diterpenoids celastrus; kaurane diterpenoids; kaurane ... See more keywords
New prenylated flavonoid glycosides from the stems of Celastrus orbiculatus with their anti-tumor activities
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DOI: 10.1080/14786419.2021.2022671
Abstract: Abstract Two new prenylated flavonoid glycosides (1-2), together with five known compounds (3-7) were isolated from the EtOAc-soluble extract of the stems of Celastrus orbiculatus. The structures of new compounds were elucidated with spectroscopic and… read more here.
Keywords: prenylated flavonoid; stems celastrus; flavonoid glycosides; celastrus orbiculatus ... See more keywords
Triptonoterpene, a Natural Product from Celastrus orbiculatus Thunb, Has Biological Activity against the Metastasis of Gastric Cancer Cells
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DOI: 10.3390/molecules27228005
Abstract: Cancer is one of the greatest threats to human health. Gastric cancer (GC) is the fifth most common malignant tumor in the world. Invasion and metastasis are the major difficulties in the treatment of GC.… read more here.
Keywords: metastasis; orbiculatus thunb; gastric cancer; invasion ... See more keywords
Celastrus orbiculatus extract suppresses the epithelial-mesenchymal transition by mediating cytoskeleton rearrangement via inhibition of the Cofilin 1 signaling pathway in human gastric cancer
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DOI: 10.3892/ol.2017.6470
Abstract: Celastrus orbiculatus is a traditional medicinal plant used in the anti-inflammatory and analgesic treatment of various diseases. A previous study demonstrated that ethyl acetate extract of C. orbiculatus (COE) exhibited significant antitumor effects. However, studies… read more here.
Keywords: celastrus orbiculatus; emt; microscopy; coe ... See more keywords