RNA-binding protein CELF1 promotes cardiac hypertrophy via interaction with PEBP1 in cardiomyocytes.
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DOI: 10.1007/s00441-021-03541-5
Abstract: Cardiac hypertrophy is considered as a common pathophysiological process in various cardiovascular diseases. CUG triplet repeat-binding protein 1 (CELF1) is an RNA-binding protein that has been shown to be an important post-transcription regulator and involved… read more here.
Keywords: cardiac hypertrophy; pebp1; celf1; binding protein ... See more keywords
Promoting role of circ-Jarid2/miR-129-5p/Celf1 axis in cardiac hypertrophy
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DOI: 10.1038/s41434-020-0165-5
Abstract: Cardiac hypertrophy is imposed much pressure on heart and threatening our live. Previous study suggested that dysregulation of Celf1 is largely connecting to neonatal cardiac dysfunction. Hence, we aimed to explore the precise function and… read more here.
Keywords: cardiac hypertrophy; mir 129; hypertrophy; circ jarid2 ... See more keywords
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1
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DOI: 10.1038/s41467-017-02353-y
Abstract: Melanomas are well-known for their altered mRNA expression profiles. Yet, the specific contribution of mRNA binding proteins (mRBPs) to melanoma development remains unclear. Here we identify a cluster of melanoma-enriched genes under the control of… read more here.
Keywords: melanoma; analysis identifies; identifies melanoma; melanoma enriched ... See more keywords
CELF1 represses Doublesex1 expression via its 5’ UTR in the crustacean Daphnia magna
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DOI: 10.1371/journal.pone.0275526
Abstract: In sex determination of the crustacean Daphnia magna, male-specific expression of DM-domain transcription factor Doublesex1 (Dsx1) orchestrates the male developmental program triggered by environmental stimuli. We previously identified the CELF1 ortholog as a candidate of… read more here.
Keywords: expression; crustacean daphnia; dsx1 expression; celf1 ... See more keywords