Lysophosphatidylcholine disrupts cell adhesion and induces anoikis in hepatocytes
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14291
Abstract: Lysophosphatidylcholine (LPC), the active metabolite of palmitate, triggers hepatocyte death by activating endoplasmic reticulum stress and JNK signalling‐mediated lipoapoptosis. However, LPC‐induced cytotoxicity in hepatocytes is not well understood. Here, we found for the first time… read more here.
Keywords: adhesion; cell; anoikis hepatocytes; cell adhesion ... See more keywords
Engineering the Dynamics of Cell Adhesion Cues in Supramolecular Hydrogels for Facile Control over Cell Encapsulation and Behavior.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202008111
Abstract: The extracellular matrix (ECM) forms through hierarchical assembly of small and larger polymeric molecules into a transient, hydrogel-like fibrous network that provides mechanical support and biochemical cues to cells. Synthetic, fibrous supramolecular networks formed via… read more here.
Keywords: supramolecular hydrogels; dynamics cell; cell adhesion; cell ... See more keywords
Choline ameliorates ethanol induced alterations in tyrosine phosphorylation and distribution in detergent-resistant membrane microdomains of L1 cell adhesion molecule in vivo.
Sign Up to like & getrecommendations! Published in 2020 at "Birth defects research"
DOI: 10.1002/bdr2.1657
Abstract: BACKGROUND Exposure to ethanol during pregnancy is the cause of fetal alcohol spectrum disorder. The function of L1 cell adhesion molecule (L1), critical for proper brain development, is dependent on detergent-resistant membrane microdomains (DRM). Ethanol… read more here.
Keywords: choline; cell adhesion; adhesion molecule; ethanol induced ... See more keywords
Trans‐synaptic mechanisms orchestrated by mammalian synaptic cell adhesion molecules
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202200134
Abstract: Bidirectional trans‐synaptic signaling is essential for the formation, maturation, and plasticity of synaptic connections. Synaptic cell adhesion molecules (CAMs) are prime drivers in shaping the identities of trans‐synaptic signaling pathways. A series of recent studies… read more here.
Keywords: cell adhesion; adhesion molecules; trans synaptic; synaptic cell ... See more keywords
Comparison of SynCAM1/CADM1 PDZ interactions with MUPP1 using mammalian and bacterial pull‐down systems
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Behavior"
DOI: 10.1002/brb3.1587
Abstract: Synaptic cell adhesion molecule 1 (SynCAM1) also known as cell adhesion molecule 1 (CADM1) is a transmembrane cell adhesion protein that operates in a variety of physiological and pathological cellular contexts, and its interaction with… read more here.
Keywords: comparison syncam1; syncam1 cadm1; cadm1 pdz; cell adhesion ... See more keywords
Artemisinin upregulates neural cell adhesion molecule L1 to attenuate neurological deficits after intracerebral hemorrhage in mice
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2558
Abstract: Intracerebral hemorrhage (ICH) is a subtype of stroke and results in neurological deficits in patients without any effective treatments. Artemisinin (ART), a well‐known antimalarial Chinese medicine, exerts multiple essential roles in the central and peripheral… read more here.
Keywords: cell adhesion; neurological deficits; adhesion molecule; intracerebral hemorrhage ... See more keywords
Anti‐epithelial cell adhesion molecule RNA aptamer‐conjugated liposomal doxorubicin as an efficient targeted therapy in mice bearing colon carcinoma tumor model
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Progress"
DOI: 10.1002/btpr.3116
Abstract: To overcome the lack of selectivity and nonspecific biodistribution of drugs in the body, targeted delivery of chemotherapeutic agents with aptamers is a very effective method. In this strategy, aptamers could be specifically identified and… read more here.
Keywords: epithelial cell; anti epithelial; cell adhesion; cell ... See more keywords
The role of cell adhesion in hematopoiesis and leukemogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28636
Abstract: The cells of the bone marrow microenvironment are emerging as important contributors and regulators of normal hematopoiesis. This microenvironment is perturbed during leukemogenesis, and evidence points toward a bidirectional communication between leukemia cells and the… read more here.
Keywords: hematopoiesis; leukemogenesis; cell adhesion; role ... See more keywords
Covalent Attachment of Fibronectin onto Emulsion-Templated Porous Polymer Scaffolds Enhances Human Endometrial Stromal Cell Adhesion, Infiltration, and Function.
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201800351
Abstract: A novel strategy for the surface functionalization of emulsion-templated highly porous (polyHIPE) materials as well as its application to in vitro 3D cell culture is presented. A heterobifunctional linker that consists of an amine-reactive N-hydroxysuccinimide… read more here.
Keywords: human endometrial; cell adhesion; spectroscopy; emulsion templated ... See more keywords
Synthesis and Characterization of Cationic Hydrogels from Thiolated Copolymers for Independent Manipulation of Mechanical and Chemical Properties of Cell Substrates.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202100453
Abstract: Cells sense both mechanical and chemical properties in their environment and respond to these inputs with altered phenotypes. Precise and selective experimental manipulations of these environmental cues require biocompatible synthetic materials, for which multiple properties… read more here.
Keywords: cell adhesion; cationic; mechanical chemical; chemical properties ... See more keywords
Photolithographically Patterned Cell-Repellent PEG-b-PTHPMA Diblock Copolymer for Guided Cell Adhesion and Growth.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200301
Abstract: Surfaces for guided cell adhesion and growth are indispensable in several diagnostic and therapeutic applications. Towards this direction, four diblock copolymers comprising polyethylene glycol (PEG) and poly(2-tetrahydropyranyl methacrylate) (PTHPMA) were synthesized employing PEG macroinitiators of… read more here.
Keywords: cell adhesion; peg; cell; adhesion growth ... See more keywords