Lysophosphatidylcholine disrupts cell adhesion and induces anoikis in hepatocytes
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14291
Abstract: Lysophosphatidylcholine (LPC), the active metabolite of palmitate, triggers hepatocyte death by activating endoplasmic reticulum stress and JNK signalling‐mediated lipoapoptosis. However, LPC‐induced cytotoxicity in hepatocytes is not well understood. Here, we found for the first time… read more here.
Keywords: adhesion; cell; anoikis hepatocytes; cell adhesion ... See more keywords
Enhanced Cell Adhesion Properties of a Collagen‐Mimicking Peptide Through Site‐Specific L‐DOPA Incorporation
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202414899
Abstract: Collagen, a key structural protein in the extracellular matrix (ECM), provides essential physical and biological support for cells, making it indispensable in tissue engineering (TE). Producing collagen‐mimicking polypeptides (CMPs) in E. coli offers advantages such… read more here.
Keywords: collagen mimicking; enhanced cell; collagen; cell adhesion ... See more keywords
Holistic Analysis of Material Properties in Phylogenetically Diverse Spider Silks and Their Influence on Cell Adhesion
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202415945
Abstract: Reconstruction of long‐segment peripheral nerve gaps remains a clinical challenge, as neither autografts nor FDA‐approved nerve conduits achieve satisfactory functional recovery. Conduits filled with native Trichonephila dragline silk show promise for nerve defects exceeding the… read more here.
Keywords: diverse spider; silk; cell adhesion; spider ... See more keywords
Engineering the Dynamics of Cell Adhesion Cues in Supramolecular Hydrogels for Facile Control over Cell Encapsulation and Behavior.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202008111
Abstract: The extracellular matrix (ECM) forms through hierarchical assembly of small and larger polymeric molecules into a transient, hydrogel-like fibrous network that provides mechanical support and biochemical cues to cells. Synthetic, fibrous supramolecular networks formed via… read more here.
Keywords: supramolecular hydrogels; dynamics cell; cell adhesion; cell ... See more keywords
Choline ameliorates ethanol induced alterations in tyrosine phosphorylation and distribution in detergent-resistant membrane microdomains of L1 cell adhesion molecule in vivo.
Sign Up to like & getrecommendations! Published in 2020 at "Birth defects research"
DOI: 10.1002/bdr2.1657
Abstract: BACKGROUND Exposure to ethanol during pregnancy is the cause of fetal alcohol spectrum disorder. The function of L1 cell adhesion molecule (L1), critical for proper brain development, is dependent on detergent-resistant membrane microdomains (DRM). Ethanol… read more here.
Keywords: choline; cell adhesion; adhesion molecule; ethanol induced ... See more keywords
Trans‐synaptic mechanisms orchestrated by mammalian synaptic cell adhesion molecules
Sign Up to like & getrecommendations! Published in 2022 at "BioEssays"
DOI: 10.1002/bies.202200134
Abstract: Bidirectional trans‐synaptic signaling is essential for the formation, maturation, and plasticity of synaptic connections. Synaptic cell adhesion molecules (CAMs) are prime drivers in shaping the identities of trans‐synaptic signaling pathways. A series of recent studies… read more here.
Keywords: cell adhesion; adhesion molecules; trans synaptic; synaptic cell ... See more keywords
Comparison of SynCAM1/CADM1 PDZ interactions with MUPP1 using mammalian and bacterial pull‐down systems
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Behavior"
DOI: 10.1002/brb3.1587
Abstract: Synaptic cell adhesion molecule 1 (SynCAM1) also known as cell adhesion molecule 1 (CADM1) is a transmembrane cell adhesion protein that operates in a variety of physiological and pathological cellular contexts, and its interaction with… read more here.
Keywords: comparison syncam1; syncam1 cadm1; cadm1 pdz; cell adhesion ... See more keywords
Artemisinin upregulates neural cell adhesion molecule L1 to attenuate neurological deficits after intracerebral hemorrhage in mice
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2558
Abstract: Intracerebral hemorrhage (ICH) is a subtype of stroke and results in neurological deficits in patients without any effective treatments. Artemisinin (ART), a well‐known antimalarial Chinese medicine, exerts multiple essential roles in the central and peripheral… read more here.
Keywords: cell adhesion; neurological deficits; adhesion molecule; intracerebral hemorrhage ... See more keywords
Anti‐epithelial cell adhesion molecule RNA aptamer‐conjugated liposomal doxorubicin as an efficient targeted therapy in mice bearing colon carcinoma tumor model
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Progress"
DOI: 10.1002/btpr.3116
Abstract: To overcome the lack of selectivity and nonspecific biodistribution of drugs in the body, targeted delivery of chemotherapeutic agents with aptamers is a very effective method. In this strategy, aptamers could be specifically identified and… read more here.
Keywords: epithelial cell; anti epithelial; cell adhesion; cell ... See more keywords
Advanced Hydrogels: Enhancing Tissue Bioengineering with RGD Peptides and Carbon Nanomaterials
Sign Up to like & getrecommendations! Published in 2024 at "Chemmedchem"
DOI: 10.1002/cmdc.202400587
Abstract: The advancement of tissue engineering (TE) is driven by the development of scaffolds that mimic the mechanical, spatial, and biological environment of the extracellular matrix (ECM), crucial for regulating cell behavior and tissue repair. Hydrogels,… read more here.
Keywords: cell adhesion; cell; enhancing tissue; advanced hydrogels ... See more keywords
β‐Catenin localization in the ctenophore Mnemiopsis leidyi suggests an ancestral role in cell adhesion and nuclear function
Sign Up to like & getrecommendations! Published in 2025 at "Developmental Dynamics"
DOI: 10.1002/dvdy.70004
Abstract: The emergence of multicellularity in animals marks a pivotal evolutionary event which was likely enabled by molecular innovations in the way cells adhere and communicate with one another. β-catenin is significant to this transition due… read more here.
Keywords: mnemiopsis; role; cell adhesion; function ... See more keywords