Rationally Designed Highly Potent NKT Cell Agonists with Different Cytokine Selectivity through Hydrogen-Bond Interaction.
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DOI: 10.1021/acs.jmedchem.4c00782
Abstract: Synthetic α-galactosylceramide (αGalCer) and its analogues as powerful agonists for natural killer T (NKT) cell manipulation have received significant attention in immunotherapy and adjuvant development. However, identifying new potent NKT cell agonists, especially those with… read more here.
Keywords: cell agonists; cell; potent nkt; nkt cell ... See more keywords