Technological Advances in Multiscale Analysis of Single Cells in Biomedicine
Sign Up to like & getrecommendations! Published in 2019 at "Advanced Biosystems"
DOI: 10.1002/adbi.201900138
Abstract: Single‐cell analysis has recently received significant attention in biomedicine. With the advances in super‐resolution microscopy, fluorescence labeling, and nanoscale biosensing, new information may be obtained for the design of cancer diagnosis and therapeutic interventions. The… read more here.
Keywords: single cell; analysis; analysis single; multiscale analysis ... See more keywords
A Machine Learning‐Assisted Nanoparticle‐Printed Biochip for Real‐Time Single Cancer Cell Analysis
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Biosystems"
DOI: 10.1002/adbi.202000160
Abstract: Cancers are a complex conglomerate of heterogeneous cell populations with varying genotypes and phenotypes. The intercellular heterogeneity within the same tumor and intratumor heterogeneity within various tumors are the leading causes of resistance to cancer… read more here.
Keywords: machine learning; cancer; cell analysis; cell ... See more keywords
Production cell analysis and compound‐based boosting of small extracellular vesicle secretion using a generic and scalable production platform
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28322
Abstract: Extracellular vesicles (EVs) are a novel format of advanced therapeutical medicinal products (ATMPs). They can act regenerative or immune‐modulatory as cell therapy substitutes or as a platform for designer exosomes. The biotechnological production of therapeutic… read more here.
Keywords: cell; production cell; production; secretion ... See more keywords
Single‐cell analysis of nonhuman primate preimplantation development in comparison to humans and mice
Sign Up to like & getrecommendations! Published in 2021 at "Developmental Dynamics"
DOI: 10.1002/dvdy.295
Abstract: Genetic programs underlying preimplantation development and early lineage segregation are highly conserved across mammals. It has been suggested that nonhuman primates would be better model organisms for human embryogenesis, but a limited number of studies… read more here.
Keywords: preimplantation; cell analysis; single cell; preimplantation development ... See more keywords
Therapeutic Antibody Discovery in Infectious Diseases Using Single-Cell Analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-0502-3_8
Abstract: Since the discovery of mouse hybridoma technology by Kohler and Milstein in 1975, significant progress has been made in monoclonal antibody production. Advances in B cell immortalization and phage display technologies have generated a myriad… read more here.
Keywords: single cell; cell analysis; antibody discovery; cell ... See more keywords
Advances in atomic force microscopy for single-cell analysis
Sign Up to like & getrecommendations! Published in 2018 at "Nano Research"
DOI: 10.1007/s12274-018-2260-0
Abstract: Single-cell analysis has been considered as a promising way to uncover the underlying mechanisms guiding the mysteries of life activities, which considerably complements traditional ensemble assays and yields novel insights into cell biology. The advent… read more here.
Keywords: single cell; microscopy; atomic force; cell analysis ... See more keywords
Multifunctional High-Throughput Single-Cell Analysis using Reconfigurable Amplifier Array
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.2472
Abstract: In recent years, an introduction of CMOS bioelectronic systems to biotechnology gave unprecedented opportunities in extremely high-throughput (1k - 10M parallel recordings) and improved noise performance. However, recent developments of CMOS bioelectronic devices mostly focused… read more here.
Keywords: single cell; cell analysis; array; high throughput ... See more keywords
Multi-channel microfluidic chip-mass spectrometry platform for cell analysis
Sign Up to like & getrecommendations! Published in 2017 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2017.05.024
Abstract: Abstract In this review, we highlight the latest development of multi-channel microfluidic chip-mass spectrometry (chip-MS) in cell analysis and metabolite detection. Following a brief introduction about history and development of multi-channel microchip and MS combination,… read more here.
Keywords: channel microfluidic; analysis; multi channel; cell analysis ... See more keywords
Nanofluidics for single-cell analysis
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.08.100
Abstract: ABSTRACT Living single-cell analysis is vital for cell biology, disease pathology, drug discovery and medical treatment. It is of great significance to reveal the law of creature and to explore the mechanism of serious disease.… read more here.
Keywords: single cell; nanofluidics single; biology; cell analysis ... See more keywords
Unique glandular ex-vivo Th1 and Th17 receptor motifs in Sjögren's syndrome patients using single-cell analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical immunology"
DOI: 10.1016/j.clim.2018.04.009
Abstract: Primary Sjögren's syndrome (pSS) is an autoimmune disease in which the underlying cause has yet to be elucidated. The main objective of this study was to determine the T cell receptor (TCR) repertoires of individual… read more here.
Keywords: single cell; cell analysis; cell; th1 th17 ... See more keywords
Quantitative measurements in single-cell analysis: towards scalability in microbial bioprocess development.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2018.01.024
Abstract: Single-cell analysis in microfluidic cultivation devices bears a great potential for the development and optimization of industrial bioprocesses. High parallelization allows running a large number of cultivation experiments simultaneously even under quick alteration of environmental… read more here.
Keywords: single cell; quantitative measurements; cell analysis; cell ... See more keywords