Effect of Oleracein E, a Neuroprotective Tetrahydroisoquinoline, on Rotenone-Induced Parkinson's Disease Cell and Animal Models.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.6b00291
Abstract: Oleracein E (OE), a tetrahydroisoquinoline possessing potent antioxidant activity, was first isolated from a traditional Chinese medicine, Portulaca oleraea L., and is hypothesized to be a neuroprotectant. In the present study, we evaluated the effects… read more here.
Keywords: disease cell; rotenone; cell animal; parkinson disease ... See more keywords
Cell and Animal Models for Studying Hepatitis B Virus Infection and Drug Development.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology"
DOI: 10.1053/j.gastro.2018.06.093
Abstract: Many cell culture and animal models have been used to study hepatitis B virus (HBV) replication and its effects in the liver; these have facilitated development of strategies to control and clear chronic HBV infection.… read more here.
Keywords: drug development; infection; cell animal; hepatitis virus ... See more keywords
Off target effects of HIV integrase strand transfer inhibitors in cell and animal models: a scoping review.
Sign Up to like & getrecommendations! Published in 2025 at "AIDS"
DOI: 10.1097/qad.0000000000004261
Abstract: In the past decade, integrase strand transfer inhibitor (INSTI)-containing regimens have become the most widely used HIV treatment worldwide. Despite their high efficacy and tolerability, numerous adverse effects have been reported, including weight gain, neuropsychiatric… read more here.
Keywords: strand transfer; integrase strand; animal models; scoping review ... See more keywords
Evaluation of Anti-Obesity and Antidiabetic Activities of Orostachys japonicus in Cell and Animal Models
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DOI: 10.3390/ph17030357
Abstract: Orostachys japonicus is a popular traditional medicinal herb used in Asian countries. This study is focused on evaluating its role in lipid and glucose metabolism in cell and animal models to establish the plant as… read more here.
Keywords: obesity antidiabetic; japonicus; anti obesity; orostachys japonicus ... See more keywords
Cell and Animal Models for SARS-CoV-2 Research
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14071507
Abstract: During the last two years following the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, development of potent antiviral drugs and vaccines has been a global health priority. In this context, the understanding of virus… read more here.
Keywords: cov research; animal models; cell animal; models sars ... See more keywords