Immunosuppression therapy is effective for both acquired tumor-associated and primary pure red cell aplasia: a match pair case-control study
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Hematology"
DOI: 10.1007/s00277-020-04105-3
Abstract: No agreement had been reached on the treatment of patients with pure red cell aplasia (PRCA) secondary to indolent malignancies. Data was collected from patients with acquired PRCA from May, 2014 to May, 2018 in… read more here.
Keywords: red cell; tumor associated; cell aplasia; pure red ... See more keywords
Acquired amegakaryocytic thrombocytopenia and red cell aplasia in a patient with thymoma progressing to aplastic anemia successfully treated with allogenic stem cell transplantation.
Sign Up to like & getrecommendations! Published in 2018 at "Hematology/oncology and stem cell therapy"
DOI: 10.1016/j.hemonc.2017.09.001
Abstract: Association of pure red-cell aplasia with thymoma is well documented. However, acquired amegakaryocytic thrombocytopenia (AAMT) has been rarely associated with thymoma with only five reported cases in literature. We report a patient with thymoma complicated… read more here.
Keywords: red cell; stem cell; cell aplasia; cell ... See more keywords
Sirolimus is effective for refractory/relapsed/intolerant acquired pure red cell aplasia: results of a prospective single-institutional trial
Sign Up to like & getrecommendations! Published in 2022 at "Leukemia"
DOI: 10.1038/s41375-022-01532-1
Abstract: Some patients with acquired pure red cell aplasia (aPRCA) have no response or are intolerant to cyclosporine A. From April 2017 to August 2020, patients diagnosed with aPRCA at Peking Union Medical College Hospital who… read more here.
Keywords: sirolimus effective; red cell; cell aplasia; pure red ... See more keywords
Clonal hematopoiesis in adult pure red cell aplasia
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-81890-5
Abstract: Idiopathic pure red cell aplasia (PRCA) and secondary PRCA associated with thymoma and large granular lymphocyte leukemia are generally considered to be immune-mediated. The PRCA2004/2006 study showed that poor responses to immunosuppression and anemia relapse… read more here.
Keywords: red cell; clonal hematopoiesis; prca; pure red ... See more keywords
Somatic mutations in acquired pure red cell aplasia.
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in hematology"
DOI: 10.1053/j.seminhematol.2022.07.001
Abstract: Acquired pure red cell aplasia (PRCA) is a syndrome characterized by anemia and a marked reduction of erythroid progenitor cells with various etiologies. The 3 major subtypes of PRCA are idiopathic PRCA, large granular lymphocytic… read more here.
Keywords: red cell; cell aplasia; cell; acquired pure ... See more keywords
Refractory Pure Red Cell Aplasia Manifesting as Deficiency of Adenosine Deaminase 2.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000000805
Abstract: Primary progress has been made in the last 2 years, particularly in finding novel disease-causing genes for a number of autoinflammatory diseases and primary immunodeficiencies. Whole-exome sequencing has dramatically increased the pace at which causative… read more here.
Keywords: red cell; cell aplasia; adenosine deaminase; pure red ... See more keywords
Resolution of epoetin‐induced pure red cell aplasia, successful re‐challenge with roxadustat
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Laboratory Hematology"
DOI: 10.1111/ijlh.13325
Abstract: The application of erythropoietin (EPO) can bring about a rare but serious complication called anti‐EPO antibody‐mediated pure red cell aplasia (PRCA). Once the disease is diagnosed, EPO administration should be stopped immediately. However, after the… read more here.
Keywords: epo antibody; red cell; epo; anti epo ... See more keywords
Pure Red Cell Aplasia following ABO-Mismatched Allogeneic Hematopoietic Stem Cell Transplantation: Resolution with Daratumumab Treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Acta haematologica"
DOI: 10.1159/000515257
Abstract: Pure red cell aplasia (PRCA) can potentially occur after allogeneic hematopoietic stem cell transplantation (allo-HSCT) if recipient and donor ABO blood groups are mismatched, with the recipient having isoagglutinins against the donor blood group. Patient… read more here.
Keywords: red cell; treatment; abo; cell aplasia ... See more keywords
HESTER: A Phase II Study Evaluating Efficacy and Safety of Tisagenlecleucel Reinfusion in Pediatric and Young Adult Patients with Acute Lymphoblastic Leukemia Experiencing Loss of B-Cell Aplasia
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-136340
Abstract: Background: Tisagenlecleucel is an anti-CD19 chimeric antigen receptor (CAR)-T cell therapy approved for pediatric and young adult patients with relapsed/refractory (r/r) B-cell acute lymphoblastic leukemia (B-ALL) and adult patients with r/r diffuse large B-cell lymphoma.… read more here.
Keywords: loss cell; reinfusion; efficacy; cell aplasia ... See more keywords
Pure red cell aplasia secondary to rheumatoid arthritis: a case report
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Case Reports"
DOI: 10.1186/s13256-021-03141-5
Abstract: Background Rheumatoid arthritis is a common autoimmune disease with many extra-articular manifestations. Pure red cell aplasia is a rare manifestation of rheumatoid arthritis and is sparsely documented in the literature, with a variable clinical outcome… read more here.
Keywords: rheumatoid arthritis; arthritis; red cell; cell aplasia ... See more keywords
Successful Treatment of Antibody-mediated Pure Red Cell Aplasia Induced by Continuous Erythropoietin Receptor Activator with Prednisolone.
Sign Up to like & getrecommendations! Published in 2021 at "Internal medicine"
DOI: 10.2169/internalmedicine.8823-21
Abstract: Pure red cell aplasia (PRCA) associated with erythropoiesis-stimulating agents (ESAs), which were first reported in 1998, usually occurs with subcutaneous administration of epoetin alfa (Eprex®). Improvements in ESA storage, handling, and administration methods have reduced… read more here.
Keywords: continuous erythropoietin; red cell; cell aplasia; pure red ... See more keywords