Immunosuppression therapy is effective for both acquired tumor-associated and primary pure red cell aplasia: a match pair case-control study
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Hematology"
DOI: 10.1007/s00277-020-04105-3
Abstract: No agreement had been reached on the treatment of patients with pure red cell aplasia (PRCA) secondary to indolent malignancies. Data was collected from patients with acquired PRCA from May, 2014 to May, 2018 in… read more here.
Keywords: red cell; tumor associated; cell aplasia; pure red ... See more keywords
Efficacy and influencing factors of immunosuppressive therapy for pure red cell aplasia: meta-analysis and systematic review
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DOI: 10.1007/s00277-025-06315-z
Abstract: Acquired pure red cell aplasia (aPRCA) is a rare hematological syndrome characterized by anemia and a significant reduction in erythroid progenitor cells. Immunosuppressive therapy (IST), including Corticosteroids (CS), Cyclosporine (CsA), and cyclophosphamide (CYC), is the… read more here.
Keywords: treatment; immunosuppressive therapy; pure red; efficacy ... See more keywords
Epidemiologic sequential analysis of pure red blood cell aplasia and T-cell large granular lymphocyte leukemia in Korea
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Hematology"
DOI: 10.1007/s00277-025-06406-x
Abstract: Pure red cell aplasia (PRCA) is a rare hematologic syndrome characterized by anemia with marked reticulocytopenia and, in Asia, is often accompanied by T-cell large granular lymphocyte leukemia (T-LGL). Minimal research has been done on… read more here.
Keywords: pure red; cell large; cell; cell aplasia ... See more keywords
Acquired amegakaryocytic thrombocytopenia and red cell aplasia in a patient with thymoma progressing to aplastic anemia successfully treated with allogenic stem cell transplantation.
Sign Up to like & getrecommendations! Published in 2018 at "Hematology/oncology and stem cell therapy"
DOI: 10.1016/j.hemonc.2017.09.001
Abstract: Association of pure red-cell aplasia with thymoma is well documented. However, acquired amegakaryocytic thrombocytopenia (AAMT) has been rarely associated with thymoma with only five reported cases in literature. We report a patient with thymoma complicated… read more here.
Keywords: red cell; stem cell; cell aplasia; cell ... See more keywords
Sirolimus is effective for refractory/relapsed/intolerant acquired pure red cell aplasia: results of a prospective single-institutional trial
Sign Up to like & getrecommendations! Published in 2022 at "Leukemia"
DOI: 10.1038/s41375-022-01532-1
Abstract: Some patients with acquired pure red cell aplasia (aPRCA) have no response or are intolerant to cyclosporine A. From April 2017 to August 2020, patients diagnosed with aPRCA at Peking Union Medical College Hospital who… read more here.
Keywords: sirolimus effective; red cell; cell aplasia; pure red ... See more keywords
Clonal hematopoiesis in adult pure red cell aplasia
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DOI: 10.1038/s41598-021-81890-5
Abstract: Idiopathic pure red cell aplasia (PRCA) and secondary PRCA associated with thymoma and large granular lymphocyte leukemia are generally considered to be immune-mediated. The PRCA2004/2006 study showed that poor responses to immunosuppression and anemia relapse… read more here.
Keywords: red cell; clonal hematopoiesis; prca; pure red ... See more keywords
Somatic mutations in acquired pure red cell aplasia.
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in hematology"
DOI: 10.1053/j.seminhematol.2022.07.001
Abstract: Acquired pure red cell aplasia (PRCA) is a syndrome characterized by anemia and a marked reduction of erythroid progenitor cells with various etiologies. The 3 major subtypes of PRCA are idiopathic PRCA, large granular lymphocytic… read more here.
Keywords: red cell; cell aplasia; cell; acquired pure ... See more keywords
Pure red cell aplasia due to Parvovirus B19 infection and atezolizumab: case report and literature review.
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DOI: 10.1080/1750743x.2025.2549675
Abstract: The benefits of immune checkpoint inhibitor (ICI)-based treatment are tempered by immune-related adverse events (irAEs). However, various aspects of the pathogenesis of these events remain unclear. Here, we report the case of a 69-year-old patient… read more here.
Keywords: parvovirus b19; treatment; cell; cell aplasia ... See more keywords
Refractory Pure Red Cell Aplasia Manifesting as Deficiency of Adenosine Deaminase 2.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000000805
Abstract: Primary progress has been made in the last 2 years, particularly in finding novel disease-causing genes for a number of autoinflammatory diseases and primary immunodeficiencies. Whole-exome sequencing has dramatically increased the pace at which causative… read more here.
Keywords: red cell; cell aplasia; adenosine deaminase; pure red ... See more keywords
Aberrant Hematopoiesis and CD8 + T‐Cell Activation in Thymoma‐Associated Pure Red Cell Aplasia
Sign Up to like & getrecommendations! Published in 2025 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.70046
Abstract: Thymoma‐associated pure red cell aplasia (PRCA) is a rare autoimmune disorder characterized by selective erythroid lineage suppression. However, the underlying immune mechanisms remain unclear. read more here.
Keywords: associated pure; pure red; cell; cell aplasia ... See more keywords
Pure Red Cell Aplasia That Developed 13 Years After Thymoma Treatment: A Case Report and Literature Review
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DOI: 10.1111/1759-7714.70157
Abstract: A 47‐year‐old woman was diagnosed with invasive thymoma 13 years ago. She had undergone repeated surgeries, as well as chemotherapy and radiation therapy. Chemotherapy was discontinued after the patient developed normocytic anemia, which was unresponsive to… read more here.
Keywords: aplasia developed; treatment; pure red; cell aplasia ... See more keywords