Platelets are recruited to hepatocellular carcinoma tissues in a CX3CL1‐CX3CR1 dependent manner and induce tumour cell apoptosis
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12783
Abstract: The mechanisms and biological functions of migrating platelets in cancer remain largely unknown. Here, we analyzed platelet infiltration in hepatocellular carcinoma. We detected platelet extravasation in both mouse and human HCC tissues. CX3CL1 directly induced… read more here.
Keywords: hepatocellular carcinoma; hcc; platelet migration; cell apoptosis ... See more keywords
XBP1 inhibits mesangial cell apoptosis in response to oxidative stress via the PTEN/AKT pathway in diabetic nephropathy
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12655
Abstract: Diabetic nephropathy (DN) is a complication of diabetes mellitus (DM) that frequently results in renal disease, and is characterized by a variety of symptoms, including albuminuria. It has been shown that apoptosis of glomerular mesangial… read more here.
Keywords: pten akt; apoptosis; oxidative stress; cell apoptosis ... See more keywords
Nitric oxide inhibits endothelial cell apoptosis by inhibiting cysteine‐dependent SOD1 monomerization
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13362
Abstract: Endothelial cell apoptosis is an important pathophysiology in many cardiovascular diseases. The gasotransmitter nitric oxide (NO) is known to regulate cell survival and apoptosis. However, the mechanism underlying the effect of NO remains unclear. In… read more here.
Keywords: apoptosis; cell apoptosis; sod1 monomerization; endothelial cell ... See more keywords
Upregulation of the lncRNA SRLR in polycystic ovary syndrome regulates cell apoptosis and IL‐6 expression
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3507
Abstract: Increased levels of interleukin‐6 (IL‐6) contribute to the development of polycystic ovary syndrome (PCOS); in renal cell carcinoma, the long non‐coding RNA (lncRNA) SRLR upregulates IL‐6. In this study, we demonstrated that the levels of… read more here.
Keywords: polycystic ovary; lncrna srlr; cell apoptosis; ovary syndrome ... See more keywords
lncRNA‐CIR regulates cell apoptosis of chondrocytes in osteoarthritis
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27997
Abstract: Osteoarthritis (OA) is a complex chronic degenerative joint disease involving oxidative stress, inflammation, and apoptosis of chondrocytes. As decoys of micro RNAs, long non‐coding RNAs (lncRNAs) play important roles in various biological processes. This study… read more here.
Keywords: apoptosis chondrocytes; regulates cell; lncrna cir; apoptosis ... See more keywords
Silencing FUNDC1 alleviates chronic obstructive pulmonary disease by inhibiting mitochondrial autophagy and bronchial epithelium cell apoptosis under hypoxic environment
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29028
Abstract: Chronic obstructive pulmonary disease (COPD) is a major global epidemic with increasing incidence worldwide. The pathogenesis of COPD is involved with mitochondrial autophagy. Recently, it has been reported that FUN14 domain containing 1 (FUNDC1) is… read more here.
Keywords: chronic obstructive; copd; cell apoptosis; mitochondrial autophagy ... See more keywords
FOXO3a is essential for murine endometrial decidualization through cell apoptosis during early pregnancy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27167
Abstract: Embryo implantation is essential for normal pregnancy, and the process of decidualization is critical for embryo implantation. However, the mechanism of decidualization during early pregnancy is still unknown. Forkhead box O3a (FOXO3a) is the most… read more here.
Keywords: decidualization; cell apoptosis; foxo3a; early pregnancy ... See more keywords
Hypermethylation‐mediated downregulation of lncRNA PVT1 promotes granulosa cell apoptosis in premature ovarian insufficiency via interacting with Foxo3a
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30222
Abstract: Long noncoding RNA PVT1 is involved in the progression of female gynecological cancers. However, the role of PVT1 in ovarian granulosa cell apoptosis‐mediated premature ovarian insufficiency (POI) remains unclear. This study aims to elucidate the… read more here.
Keywords: granulosa cell; cell apoptosis; pvt1;
N‐acetyl cysteine‐mediated effective attenuation of methoxychlor‐induced granulosa cell apoptosis by counteracting reactive oxygen species generation in caprine ovary
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Toxicology"
DOI: 10.1002/tox.22221
Abstract: Methoxychlor (MXC), an organochloride insecticide, is a potent toxicant‐targeting female reproductive system and known to cause follicular atresia by inducing apoptosis within granulosa cells. Oxidative stress plays a pivotal role in apoptosis; thus, this study… read more here.
Keywords: granulosa; apoptosis; caprine ovary; granulosa cell ... See more keywords
Dysregulated pseudogene BNIP3P1 inhibited cell proliferation and promoted cell apoptosis in preeclampsia by acting as a competing endogenous RNA for BNIP3
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23159
Abstract: Long noncoding RNAs (lncRNAs) have been reported as critical modulators in many diseases including preeclampsia. Since the association between lncRNA BNIP3P1 and its cognate gene BNIP3 in preeclampsia has been revealed previously, this study aimed… read more here.
Keywords: cell proliferation; cell apoptosis; bnip3p1; bnip3 ... See more keywords
Cell Apoptosis and Autophagy in Renal Fibrosis.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8871-2_28
Abstract: Renal fibrosis is the final common pathway of all chronic kidney diseases progressing to end-stage renal diseases. Autophagy, a highly conserved lysosomal degradation pathway, plays important roles in maintaining cellular homeostasis in all major types… read more here.
Keywords: fibrosis; kidney diseases; cell apoptosis; renal fibrosis ... See more keywords