A case of solitary subependymal giant cell astrocytoma with histopathological anaplasia and TSC2 gene alteration
Sign Up to like & getrecommendations! Published in 2020 at "Child's Nervous System"
DOI: 10.1007/s00381-020-04839-5
Abstract: We report a case of subependymal giant cell astrocytoma (SEGA) with anaplastic histological features in a 3-year-old girl. She had no clinical manifestations of tuberous sclerosis complex (TSC) and no relevant family history. A few… read more here.
Keywords: giant cell; case solitary; cell astrocytoma; case ... See more keywords
Solitary subependymal giant cell astrocytoma: Case report and review of the literature
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2020.10.017
Abstract: Tuberous sclerosis complex (TSC) is a multisystem autosomal dominant hamartoma syndrome caused by mutations in TSC1 or TSC2 genes, leading to upregulation of cell growth signalling pathways. Subependymal giant cell astrocytomas (SEGAs) are seen almost… read more here.
Keywords: giant cell; cell astrocytoma; report; cell ... See more keywords
Subependymal Giant Cell Astrocytoma: A Surveillance, Epidemiology, and End Results Program-Based Analysis from 2004 to 2013.
Sign Up to like & getrecommendations! Published in 2018 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.06.169
Abstract: BACKGROUND Subependymal giant cell astrocytoma (SEGA) is a rare, benign neoplasm predominantly associated with tuberous sclerosis complex. Clinical outcomes have largely been conveyed via small- and medium-sized case series. METHODS With the Surveillance, Epidemiology, and… read more here.
Keywords: giant cell; age; analysis; cell astrocytoma ... See more keywords
Granular cell astrocytoma - a diagnostic conundrum.
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DOI: 10.1016/j.wneu.2020.07.139
Abstract: Granular cell astrocytoma (GCA) is an aggressive variant of astrocytoma characterised by predominantly round-to-polygonal cells with abundant eosinophilic granular cytoplasm. This tumor usually lack the morphological signatures of conventional astrocytoma and are devoid of typical… read more here.
Keywords: granular cell; diagnostic conundrum; astrocytoma diagnostic; cell astrocytoma ... See more keywords
Thyroid transcription factor-1 distinguishes subependymal giant cell astrocytoma from its mimics and supports its cell origin from the progenitor cells in the medial ganglionic eminence
Sign Up to like & getrecommendations! Published in 2017 at "Modern Pathology"
DOI: 10.1038/modpathol.2016.205
Abstract: Subependymal giant cell astrocytoma is a benign brain tumor mostly associated with tuberous sclerosis complex. However, it may be misinterpreted as other high-grade brain tumors due to the presence of large tumor cells with conspicuous… read more here.
Keywords: giant cell; cell astrocytoma; medial ganglionic; cell ... See more keywords
Experience using mTOR inhibitors for subependymal giant cell astrocytoma in tuberous sclerosis complex at a single facility
Sign Up to like & getrecommendations! Published in 2021 at "BMC Neurology"
DOI: 10.1186/s12883-021-02160-5
Abstract: Background Subependymal giant cell astrocytoma (SEGA) is occasionally seen in tuberous sclerosis complex (TSC). Two main options are currently available for treating SEGA: surgical resection or pharmacotherapy using mammalian target of rapamycin inhibitors (mTORi). We… read more here.
Keywords: giant cell; facility; cell astrocytoma; group ... See more keywords
Clinical Characteristics of Subependymal Giant Cell Astrocytoma in Tuberous Sclerosis Complex
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DOI: 10.3389/fneur.2019.00705
Abstract: Background: This study evaluated the characteristics of subependymal giant cell astrocytoma (SEGA) in patients with tuberous sclerosis complex (TSC) entered into the TuberOus SClerosis registry to increase disease Awareness (TOSCA). Methods: The study was conducted… read more here.
Keywords: sclerosis; tuberous sclerosis; giant cell; cell astrocytoma ... See more keywords
Case report: ‘Photodynamics of Subependymal Giant Cell Astrocytoma with 5-Aminolevulinic acid’
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Surgery"
DOI: 10.3389/fsurg.2022.1065979
Abstract: Subependymal Giant Cell Astrocytoma (SEGA) is a common diagnosis in patients with Tuberous Sclerosis. Although surgical treatment is often required, resection may entail a significant risk for cognitive function given the anatomical relation with critical… read more here.
Keywords: subependymal giant; cell astrocytoma; report; giant cell ... See more keywords