Single‐Cell Atlas Reveals Tumorigenic Profiles and Immune Dynamics of Adrenal Incidentalomas
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202413493
Abstract: Adrenal incidentalomas (AIs) are commonly detected endocrine lesions, identified during imaging for unrelated conditions. These lesions exhibit considerable heterogeneity and diverse clinical outcomes. This study employed single‐cell RNA sequencing to investigate tumorigenic characteristics of AIs,… read more here.
Keywords: cell atlas; single cell; profiles immune; cell ... See more keywords
IPGCA: A Comprehensive Single Cell Atlas of 1 074 127 Porcine Intestinal Cells Revealing Cellular Dynamics, Genetic Regulation, and Cross-Species Conservation.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202507882
Abstract: The porcine intestinal tract is vital for nutrient absorption, immune regulation, and various physiological processes. However, a comprehensive understanding of its cellular composition and gene regulatory landscape remains limited. Here, the Integrated Pig Gut Cell… read more here.
Keywords: cell atlas; single cell; comprehensive single; 074 127 ... See more keywords
A Single‐Cell Atlas Revealed Altered B Cells and Neutrophils Immune Signatures and Inflammatory Responses in SFTSV Infection
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Medical Virology"
DOI: 10.1002/jmv.70354
Abstract: Severe fever with thrombocytopenia syndrome virus (SFTSV) presents an emerging public threat due to its high mortality rate and ever‐expanding geographic distribution. However, characterization of SFTSV infection pathogenesis and immunological impact at single‐cell level remains… read more here.
Keywords: sftsv infection; cell atlas; single cell; cells neutrophils ... See more keywords
Revealing the Critical Regulators of Cell Identity in the Mouse Cell Atlas
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.10.045
Abstract: SUMMARY Recent progress in single-cell technologies has enabled the identification of all major cell types in mouse. However, for most cell types, the regulatory mechanism underlying their identity remains poorly understood. By computational analysis of… read more here.
Keywords: mouse cell; cell atlas; cell; cell types ... See more keywords
A single-cell atlas of Drosophila trachea reveals glycosylation-mediated Notch signaling in cell fate specification
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-46455-w
Abstract: The Drosophila tracheal system is a favorable model for investigating the program of tubular morphogenesis. This system is established in the embryo by post-mitotic cells, but also undergoes remodeling by adult stem cells. Here, we… read more here.
Keywords: cell atlas; drosophila trachea; cell; notch signaling ... See more keywords
Multimodal cell atlas of the ageing human skeletal muscle
Sign Up to like & getrecommendations! Published in 2024 at "Nature"
DOI: 10.1038/s41586-024-07348-6
Abstract: Muscle atrophy and functional decline (sarcopenia) are common manifestations of frailty and are critical contributors to morbidity and mortality in older people1. Deciphering the molecular mechanisms underlying sarcopenia has major implications for understanding human ageing2.… read more here.
Keywords: skeletal muscle; cell atlas; muscle; cell ... See more keywords
The Organoid Cell Atlas
Sign Up to like & getrecommendations! Published in 2020 at "Nature Biotechnology"
DOI: 10.1038/s41587-020-00762-x
Abstract: To the Editor — Human organoids hold tremendous potential for biomedical applications1–3 (Fig. 1a,b). These three-dimensional structures of cultured cells recapitulate important aspects of in vivo organ development and biological function. They provide tractable in… read more here.
Keywords: single cell; cell atlas; biology; human organoids ... See more keywords
A single-cell atlas of the murine limb skeleton integrating the developmental and adult stages
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-05277-6
Abstract: The recent growth of single-cell transcriptomics has made single-cell RNA sequencing (scRNA-seq) into a near-routine technique. Breakthroughs in scalability have led to the creation of organism-wide transcriptomic datasets, aiming to comprehensively profile the cell types… read more here.
Keywords: adult; cell atlas; skeleton; single cell ... See more keywords
Filling in the slate with transcriptomes for mice across ages
Sign Up to like & getrecommendations! Published in 2020 at "Lab Animal"
DOI: 10.1038/s41684-020-0635-9
Abstract: In 2018, an international consortium of researchers began filling in the ‘blank slate’ that was the mouse transcriptome with the Tabula Muris, or Mouse Cell Atlas. Using two different methods for separating cells—fluorescence-activated cell sorting… read more here.
Keywords: mice across; tabula muris; cell atlas; slate ... See more keywords
Cell Atlas technologies and insights into tissue architecture
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical Journal"
DOI: 10.1042/bcj20190341
Abstract: Since Robert Hooke first described the existence of ‘cells’ in 1665, scientists have sought to identify and further characterise these fundamental units of life. While our understanding of cell location, morphology and function has expanded… read more here.
Keywords: atlas technologies; tissue architecture; cell atlas; cell ... See more keywords
Cell atlas of the human ocular anterior segment: Tissue-specific and shared cell types
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2200914119
Abstract: The anterior segment of the eye consists of the cornea, iris, ciliary body, crystalline lens and aqueous humor outflow pathways. Together, these tissues are essential for the proper functioning of the eye. Disorders of vision… read more here.
Keywords: cell; cell atlas; cell types; anterior segment ... See more keywords