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Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-020-00286-4
Abstract: Preeclampsia (PE) is one of the main causes of maternal death and perinatal morbidity and mortality. Considering that histone deacetylase 4 (HDAC4) activity could relate to trophoblast cell motility and be antagonized by miR-29b, the…
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Keywords:
autophagy apoptosis;
hdac4;
trophoblast;
mir 29b ... See more keywords
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Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.032
Abstract: Osteoarthritis (OA) is a common chronic degenerative joint disease, and chondrocyte apoptosis is one of most important pathological changes of OA pathogenesis. Growing studies have shown that Ubiquitin-like with PHD and RING finger domains 1…
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Keywords:
pi3k;
apoptosis;
mtor signaling;
signaling pathway ... See more keywords
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Published in 2019 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-019-0402-x
Abstract: β-transducin repeat-containing protein (β-TrCP), one of the best-characterized substrate recognition components of the SKP1-CUL1-F-box (SCF) E3 ligase, has two distinct paralogs, β-TrCP1 and β-TrCP2, expressed in mammals. Through governing the ubiquitination and degradation of numerous…
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Keywords:
cross talk;
degradation;
growth;
trcp1 trcp2 ... See more keywords
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Published in 2018 at "Nanoscale"
DOI: 10.1039/c8nr05770b
Abstract: Autophagy represents an important cellular response to nanoparticles (NPs), whose modulation holds great promise for developing nanomedicine. Here, we systematically studied cell autophagy responses elicited by the NP-protein corona with diverse protein corona types surrounding…
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Keywords:
serum protein;
corona responsive;
protein corona;
cell autophagy ... See more keywords
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Published in 2018 at "Environmental Microbiology"
DOI: 10.1111/1462-2920.13998
Abstract: Phosphatidylcholine (PC) plays an important role in maintaining membrane integrity and functionality. In this study, two key genes (Mrpct and Mrpem) putatively involved in the cytidine diphosphate (CDP)-choline and phosphatidylethanolamine N-methyltransferase (PEMT) pathways for PC…
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Keywords:
phosphatidylcholine;
metarhizium robertsii;
cell autophagy;
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1
Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/2798070
Abstract: Aim Pancreatic cancer is one of the most quickly fatal cancers around the world. Burgeoning researches have begun to prove that mitochondria play a crucial role in cancer treatment. Mitofusin2 (Mfn2) plays an indispensable role…
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Keywords:
pancreatic cancer;
pi3k akt;
cancer;
autophagy pancreatic ... See more keywords
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Published in 2018 at "Stroke"
DOI: 10.1161/strokeaha.117.018637
Abstract: Background and Purpose— Inflammatory cells play a significant role in secondary injury after ischemic stroke. Recent studies have suggested that a lack of autophagy in myeloid cells causes augmented proinflammatory cytokine release and prolonged inflammation…
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Keywords:
autophagy myeloid;
myeloid lineage;
injury;
cell autophagy ... See more keywords
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Published in 2017 at "Tumor Biology"
DOI: 10.1177/1010428317708532
Abstract: Sirtuin 6, a member of sirtuin family, is generally regarded as a tumor suppressor as it participates in suppressing hypoxia-inducible factor 1α and MYC transcription activity by deacetylating H3K9 (histone H3 lysine 9) and H3K56…
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Keywords:
esophageal cancer;
sirtuin plays;
cancer cells;
cancer ... See more keywords
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Published in 2018 at "Endocrinology"
DOI: 10.1210/en.2017-03273
Abstract: Nearly 100 years have passed since Frederick Banting and Charles Best first discovered and purified insulin. Their discovery and subsequent improvements revolutionized the treatment of diabetes, and the field continues to move at an ever-faster…
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Keywords:
autophagy diabetes;
diabetes pathogenesis;
type;
cell autophagy ... See more keywords
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Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2021.67.5.5
Abstract: Tuberculosis is a highly contagious infectious disease. Mycobacterium tuberculosis infection is the main cause of tuberculosis. During the infection of M. tuberculosis, the expression of the resistance gene BAG2 will change, and miR-27b will play…
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Keywords:
tuberculosis;
cell autophagy;
tuberculosis infection;
bag2 ... See more keywords
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Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.21138
Abstract: Currently only docetaxel has been approved to be used in the chemotherapy of prostate cancer and new drugs are urgent need. Salen-Mn is a novel type of synthetic reagent bionic and exerts remarkable anticancer activities.…
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Keywords:
cell autophagy;
cell;
prostate cancer;
cancer cells ... See more keywords