HDAC4 Knockdown Induces Preeclampsia Cell Autophagy and Apoptosis by miR-29b
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-020-00286-4
Abstract: Preeclampsia (PE) is one of the main causes of maternal death and perinatal morbidity and mortality. Considering that histone deacetylase 4 (HDAC4) activity could relate to trophoblast cell motility and be antagonized by miR-29b, the… read more here.
Keywords: autophagy apoptosis; hdac4; trophoblast; mir 29b ... See more keywords
Silencing UHRF1 enhances cell autophagy to prevent articular chondrocytes from apoptosis in osteoarthritis through PI3K/AKT/mTOR signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.06.032
Abstract: Osteoarthritis (OA) is a common chronic degenerative joint disease, and chondrocyte apoptosis is one of most important pathological changes of OA pathogenesis. Growing studies have shown that Ubiquitin-like with PHD and RING finger domains 1… read more here.
Keywords: pi3k; apoptosis; mtor signaling; signaling pathway ... See more keywords
The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth
Sign Up to like & getrecommendations! Published in 2019 at "Cell Death and Differentiation"
DOI: 10.1038/s41418-019-0402-x
Abstract: β-transducin repeat-containing protein (β-TrCP), one of the best-characterized substrate recognition components of the SKP1-CUL1-F-box (SCF) E3 ligase, has two distinct paralogs, β-TrCP1 and β-TrCP2, expressed in mammals. Through governing the ubiquitination and degradation of numerous… read more here.
Keywords: cross talk; degradation; growth; trcp1 trcp2 ... See more keywords
Serum protein corona-responsive autophagy tuning in cells.
Sign Up to like & getrecommendations! Published in 2018 at "Nanoscale"
DOI: 10.1039/c8nr05770b
Abstract: Autophagy represents an important cellular response to nanoparticles (NPs), whose modulation holds great promise for developing nanomedicine. Here, we systematically studied cell autophagy responses elicited by the NP-protein corona with diverse protein corona types surrounding… read more here.
Keywords: serum protein; corona responsive; protein corona; cell autophagy ... See more keywords
Diverse effect of phosphatidylcholine biosynthetic genes on phospholipid homeostasis, cell autophagy and fungal developments in Metarhizium robertsii
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Microbiology"
DOI: 10.1111/1462-2920.13998
Abstract: Phosphatidylcholine (PC) plays an important role in maintaining membrane integrity and functionality. In this study, two key genes (Mrpct and Mrpem) putatively involved in the cytidine diphosphate (CDP)-choline and phosphatidylethanolamine N-methyltransferase (PEMT) pathways for PC… read more here.
Keywords: phosphatidylcholine; metarhizium robertsii; cell autophagy;
Mitofusin2 Induces Cell Autophagy of Pancreatic Cancer through Inhibiting the PI3K/Akt/mTOR Signaling Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/2798070
Abstract: Aim Pancreatic cancer is one of the most quickly fatal cancers around the world. Burgeoning researches have begun to prove that mitochondria play a crucial role in cancer treatment. Mitofusin2 (Mfn2) plays an indispensable role… read more here.
Keywords: pancreatic cancer; pi3k akt; cancer; autophagy pancreatic ... See more keywords
Role of Myeloid Lineage Cell Autophagy in Ischemic Brain Injury
Sign Up to like & getrecommendations! Published in 2018 at "Stroke"
DOI: 10.1161/strokeaha.117.018637
Abstract: Background and Purpose— Inflammatory cells play a significant role in secondary injury after ischemic stroke. Recent studies have suggested that a lack of autophagy in myeloid cells causes augmented proinflammatory cytokine release and prolonged inflammation… read more here.
Keywords: autophagy myeloid; myeloid lineage; injury; cell autophagy ... See more keywords
Sirtuin 6 plays an oncogenic role and induces cell autophagy in esophageal cancer cells
Sign Up to like & getrecommendations! Published in 2017 at "Tumor Biology"
DOI: 10.1177/1010428317708532
Abstract: Sirtuin 6, a member of sirtuin family, is generally regarded as a tumor suppressor as it participates in suppressing hypoxia-inducible factor 1α and MYC transcription activity by deacetylating H3K9 (histone H3 lysine 9) and H3K56… read more here.
Keywords: esophageal cancer; sirtuin plays; cancer cells; cancer ... See more keywords
β-Cell Autophagy in Diabetes Pathogenesis.
Sign Up to like & getrecommendations! Published in 2018 at "Endocrinology"
DOI: 10.1210/en.2017-03273
Abstract: Nearly 100 years have passed since Frederick Banting and Charles Best first discovered and purified insulin. Their discovery and subsequent improvements revolutionized the treatment of diabetes, and the field continues to move at an ever-faster… read more here.
Keywords: autophagy diabetes; diabetes pathogenesis; type; cell autophagy ... See more keywords
BAG2-activated cell autophagy and mir-27b dynamic regulation mechanism during Mycobacterium tuberculosis infection.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2021.67.5.5
Abstract: Tuberculosis is a highly contagious infectious disease. Mycobacterium tuberculosis infection is the main cause of tuberculosis. During the infection of M. tuberculosis, the expression of the resistance gene BAG2 will change, and miR-27b will play… read more here.
Keywords: tuberculosis; cell autophagy; tuberculosis infection; bag2 ... See more keywords
Salen-Mn compounds induces cell apoptosis in human prostate cancer cells through promoting AMPK activity and cell autophagy
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.21138
Abstract: Currently only docetaxel has been approved to be used in the chemotherapy of prostate cancer and new drugs are urgent need. Salen-Mn is a novel type of synthetic reagent bionic and exerts remarkable anticancer activities.… read more here.
Keywords: cell autophagy; cell; prostate cancer; cancer cells ... See more keywords