Mechanochemical Crosstalk Produces Cell-Intrinsic Patterning of the Cortex to Orient the Mitotic Spindle
Sign Up to like & getrecommendations! Published in 2020 at "Current Biology"
DOI: 10.1016/j.cub.2020.06.098
Abstract: Summary Proliferating animal cells are able to orient their mitotic spindles along their interphase cell axis, setting up the axis of cell division, despite rounding up as they enter mitosis. This has previously been attributed… read more here.
Keywords: cell axis; cell; mechanochemical crosstalk; orient mitotic ... See more keywords
Interleukin-2-regulatory T cell axis critically regulates maintenance of hematopoietic stem cells
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DOI: 10.18632/oncotarget.16377
Abstract: The role of IL-2 in HSC maintenance is unknown. Here we show that Il2−/− mice develop severe anomalies in HSC maintenance leading to defective hematopoiesis. Whereas, lack of IL-2 signaling was detrimental for lympho- and… read more here.
Keywords: cell axis; hematopoiesis; maintenance; hsc maintenance ... See more keywords
The Liver–α-Cell Axis in Health and in Disease
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DOI: 10.2337/dbi22-0004
Abstract: Glucagon and insulin are the main regulators of blood glucose. While the actions of insulin are extensively mapped, less is known about glucagon. Besides glucagon’s role in glucose homeostasis, there are additional links between the… read more here.
Keywords: cell axis; liver cell; glucagon; amino acid ... See more keywords