Articles with "cell based" as a keyword



Real‐world clinical experience with serum MOG and AQP4 antibody testing by live versus fixed cell‐based assay

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Published in 2025 at "Annals of Clinical and Translational Neurology"

DOI: 10.1002/acn3.52310

Abstract: To assess the real‐world performance of a live (LCBA) versus a fixed (FCBA) cell‐based assay for the detection of serum antibodies directed against myelin oligodendrocyte glycoprotein (MOG‐IgG) and aquaporin‐4 (AQP4‐IgG). read more here.

Keywords: real world; versus fixed; cell based; based assay ... See more keywords

Integrating Additive Manufacturing Techniques to Improve Cell‐Based Implants for the Treatment of Type 1 Diabetes

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Published in 2022 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202200243

Abstract: The increasing global prevalence of endocrine diseases like type 1 diabetes mellitus (T1DM) elevates the need for cellular replacement approaches, which can potentially enhance therapeutic durability and outcomes. Central to any cell therapy is the… read more here.

Keywords: cell based; cell; manufacturing techniques; type diabetes ... See more keywords

Cell-Based Biomaterials for COVID-19 Prevention and Therapy.

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Published in 2023 at "Advanced healthcare materials"

DOI: 10.1002/adhm.202300404

Abstract: Coronavirus disease 2019 (COVID-19) continues to threaten human health, economic development and national security. Although many vaccines and drugs have been explored to fight against the major pandemic, their efficacy and safety still need to… read more here.

Keywords: cell based; prevention therapy; covid prevention; based biomaterials ... See more keywords

High-throughput downstream process development for cell-based products using aqueous two-phase systems (ATPS) - A case study.

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Published in 2017 at "Biotechnology journal"

DOI: 10.1002/biot.201600587

Abstract: The availability of preparative-scale downstream processing strategies for cell-based products presents a critical juncture between fundamental research and clinical development. Aqueous two-phase systems (ATPS) present a gentle, scalable, label-free, and cost-effective method for cell purification,… read more here.

Keywords: phase; cell based; downstream; cell ... See more keywords
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HepG2 as promising cell-based model for biosynthesis of long-term metabolites - exemplified for metandienone.

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Published in 2021 at "Drug testing and analysis"

DOI: 10.1002/dta.3184

Abstract: In order to detect the abuse of substances in sports, the knowledge of their metabolism is of undisputable importance. As in vivo administration of compounds faces ethical problems and might even not be applicable for… read more here.

Keywords: long term; metandienone; cell based; hepg2 cells ... See more keywords
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Understanding embryonic development for cell‐based therapies of intervertebral disc degeneration: Toward an effort to treat disc degeneration subphenotypes

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Published in 2020 at "Developmental Dynamics"

DOI: 10.1002/dvdy.217

Abstract: Chronic low back and neck pain are associated with intervertebral disc degeneration and are major contributors to the global burden of disability. New evidence now suggests that disc degeneration comprises a spectrum of subphenotypes influenced… read more here.

Keywords: based therapies; degeneration; cell based; intervertebral disc ... See more keywords

A Biofuel Cell Based on Biocatalytic Reactions of Glucose on Both Anode and Cathode Electrodes

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Published in 2017 at "Electroanalysis"

DOI: 10.1002/elan.201600706

Abstract: Biofuel cells based on electrocatalytic oxidation of NADH and reduction of H2O2 have been prepared using carbon fiber electrodes functionalized with graphene nano-flakes. The electrochemical oxidation of NADH was catalyzed by Meldola's blue (MB), while… read more here.

Keywords: biofuel cell; biofuel; cell based; based biocatalytic ... See more keywords

Cell-Based Bioassay to Screen Environmental Chemicals and Human Serum for Total Glucocorticogenic Activity.

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Published in 2020 at "Environmental toxicology and chemistry"

DOI: 10.1002/etc.4903

Abstract: Glucocorticoids (GCs) are steroid hormones that have systemic effects that are mediated by the glucocorticoid receptor (GR). Environmental chemicals that disrupt GR signaling and/or GC homeostasis could adversely affect the health of human and non-human… read more here.

Keywords: chemicals human; glucocorticogenic activity; human serum; cell based ... See more keywords

Continuing Challenges in Advancing Preclinical Science in Skeletal Cell‐Based Therapies and Tissue Regeneration

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Published in 2018 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.3578

Abstract: Cell‐based therapies hold much promise for musculoskeletal medicine; however, this rapidly growing field faces a number of challenges. Few of these therapies have proven clinical benefit, and an insufficient regulatory environment has allowed for widespread… read more here.

Keywords: continuing challenges; science; based therapies; cell based ... See more keywords

Much‐Needed Clarification and Guidance on Cell‐Based Therapies for Musculoskeletal Disorders

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Published in 2019 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.3841

Abstract: Within the last 30 years, there have beenmany advancements within the field of stem cell biology, and controversies regarding their clinical implementation make the joint American Society forBoneandMineralResearch (ASBMR)andtheOrthopaedic Research Society (ORS) Task Force by… read more here.

Keywords: cell based; stem cell; stem; cell ... See more keywords

NK Cell‐Based Cancer Immunotherapies: Current Progress, Challenges and Emerging Opportunities

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Published in 2024 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.70044

Abstract: Natural killer (NK) cells are vital innate immune cells that play a crucial role in cancer therapy. They are targeted by therapies designed to modulate, retain, and enhance their antitumor function in vivo. In addition… read more here.

Keywords: cancer; cancer immunotherapies; cell based; based cancer ... See more keywords