Utilization of cytologic cell blocks for targeted sequencing of solid tumors
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DOI: 10.1002/cam4.5261
Abstract: Targeted sequencing of cytologic samples has significantly increased in recent years. With increasing numbers of clinical trials for variant specific therapeutics, validating a comprehensive assay for cytologic samples has become clinically important. read more here.
Keywords: cytologic; cytologic cell; utilization cytologic; cell blocks ... See more keywords
Preanalytic specimen triage: Smears, cell blocks, cytospin preparations, transport media, and cytobanking
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DOI: 10.1002/cncy.21850
Abstract: With increasing requests for the evaluation of prognostic and predictive molecular biomarkers, great attention must be paid to the preanalytical issues regarding sample quality and DNA/RNA yield from all different types of cytological preparations. The… read more here.
Keywords: specimen triage; dna rna; preanalytic specimen; cytology ... See more keywords
PD‐L1 expression in NSCLC: Role of cell blocks and concordance between samples
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DOI: 10.1002/dc.24646
Abstract: PD‐L1 immunohistochemistry is currently performed in patients with advanced non‐small cell lung carcinoma (NSCLC) to identify responders to immune checkpoint inhibitors. Cell blocks from fine needle aspiration of NSCLC are frequently used for diagnostic purposes.… read more here.
Keywords: nsclc role; concordance; expression nsclc; cell ... See more keywords
Ancillary studies on cell blocks from fine needle aspiration specimens of salivary gland lesions: A multi‐institutional study
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DOI: 10.1002/dc.24939
Abstract: Ancillary studies are commonly performed on cell blocks prepared from fine‐needle aspiration (FNA) specimens. There are limited studies in application of ancillary studies on cell blocks from salivary gland (SG) FNAs. This multi‐institutional study evaluates… read more here.
Keywords: cell blocks; studies cell; fine needle; needle aspiration ... See more keywords
Clinical and cytopathological factors affecting the cellularity of urinary cell blocks and the implication for diagnosis and follow‐up of urinary bladder urothelial carcinoma
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DOI: 10.1111/cyt.12580
Abstract: The methodology of cell blocks (CBs) has long been an integrated part of cytology. However, there are very few data on CBs derived from urine. Their main disadvantage is a lack of cellularity, which limits… read more here.
Keywords: clinical cytopathological; cellularity; factors affecting; cytopathological factors ... See more keywords
The utility of cell blocks for international cytopathology teleconsultation by whole slide imaging
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DOI: 10.1111/cyt.12800
Abstract: Telecytology for second opinion consultation has largely been limited by technical issues, such as the inability to focus well on cellular material. Nevertheless, international telecytology consultation was undertaken at our institution with partners in China… read more here.
Keywords: teleconsultation; blocks international; cytopathology; cell ... See more keywords
Correlation of p16 immunostaining in cell‐blocks with corresponding tissue specimens for squamous cell carcinomas of the oropharynx
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DOI: 10.1111/cyt.12911
Abstract: The goal of this study was to evaluate the performance of p16 staining in cell‐blocks vs tissue specimens as a surrogate marker for human papillomavirus (HPV) status in oropharyngeal squamous cell carcinomas. read more here.
Keywords: squamous cell; tissue specimens; cell; cell carcinomas ... See more keywords
Quality of cell blocks prepared from residual pleural effusion and bronchial washing samples for immunocytochemistry
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DOI: 10.1111/cyt.13228
Abstract: Cell blocks (CBs) enable the long‐term preservation of cytological samples. The aim of this study was to analyse the quality of CBs prepared from leftover fluid from lung adenocarcinoma pleural effusion samples and residual bronchial… read more here.
Keywords: cell blocks; bronchial washing; pleural effusion; quality ... See more keywords
Manufactured Cell Blocks: Turning Smears into Sections
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DOI: 10.1159/000493907
Abstract: Whilst cytological smears are still the basis of cytodiagnosis, there is an increasing role for ancillary testing. Specimens obtained are not always optimal, often with limited material for ancillary studies. Several reports have described the… read more here.
Keywords: manufactured cell; turning smears; blocks turning; material ... See more keywords
Improving diagnosis of tuberculous lymphadenitis by combination of cytomorphology and MPT64 immunostaining on cell blocks from the fine needle aspirates
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DOI: 10.1371/journal.pone.0276064
Abstract: Background Extra pulmonary tuberculosis (EPTB) constitutes 18% of all tuberculosis (TB) cases and tuberculous lymphadenitis (TBL) constitutes 20–40% of EPTB. Diagnosis of TBL is challenging because of the paucibacillary nature of the disease. Objective To… read more here.
Keywords: mpt64; cell blocks; tuberculous lymphadenitis; fine needle ... See more keywords
Refined Diagnosis of Pleural Effusions by Immunocytochemistry of Cell Blocks
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DOI: 10.21873/anticanres.16204
Abstract: Background/Aim: The main objective of microscopic examination of pleural effusions is to ascertain the presence of malignant cells. Effusions prepared routinely using May–Grünwald–Giemsa (MGG)- and Papanicolaou (PAP)-staining can, in a number of cases, provide inconclusive… read more here.
Keywords: cell; cell blocks; refined diagnosis; pleural effusions ... See more keywords