Microtubule-Targeting Agents Eribulin and Paclitaxel Differentially Affect Neuronal Cell Bodies in Chemotherapy-Induced Peripheral Neuropathy
Sign Up to like & getrecommendations! Published in 2017 at "Neurotoxicity Research"
DOI: 10.1007/s12640-017-9729-6
Abstract: Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of anticancer treatment with microtubule-targeted agents (MTAs). The frequency of severe CIPN, which can be dose limiting and even life threatening, varies widely among different MTAs.… read more here.
Keywords: microtubule; peripheral neuropathy; induced peripheral; chemotherapy induced ... See more keywords
Retrograde signaling via axonal transport through signaling endosomes.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2019.10.001
Abstract: Neurons extend axons far from cell bodies, and retrograde communications from distal axons to cell bodies and/or dendrites play critical roles in the development and maintenance of neuronal circuits. In neurotrophin signaling, the retrograde axonal… read more here.
Keywords: neurotrophin signaling; retrograde signaling; signaling endosomes; axonal transport ... See more keywords
Macrophage biology in the peripheral nervous system after injury
Sign Up to like & getrecommendations! Published in 2019 at "Progress in Neurobiology"
DOI: 10.1016/j.pneurobio.2018.12.001
Abstract: HighlightsAfter axotomy macrophage were seen only as being involved in Wallerian degeneration.In addition, macrophages accumulate around axotomized neuronal cell bodies.Macrophages enter into distal nerves and ganglia in response to the chemokine CCL2.Macrophages in peripheral ganglia… read more here.
Keywords: response; biology; macrophage; lesion ... See more keywords
Differential immunostaining patterns of transient receptor potential (TRP) ion channels in the rat nodose ganglion
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Anatomy"
DOI: 10.1111/joa.13656
Abstract: Vagal afferents regulate numerous physiological functions including arterial blood pressure, heart rate, breathing, and nociception. Cell bodies of vagal afferents reside in the inferior vagal (nodose) ganglia and their stimulation by various means is being… read more here.
Keywords: cell bodies; cell; nodose ganglia; trp channels ... See more keywords
Ultrastructural evidence of microglial heterogeneity in Alzheimer’s disease amyloid pathology
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-019-1473-9
Abstract: BackgroundAlzheimer’s disease (AD) is the most common neurodegenerative disease, characterized by the deposition of extracellular fibrillar amyloid β (fΑβ) and the intracellular accumulation of neurofibrillary tangles. As AD progresses, Aβ drives a robust and prolonged… read more here.
Keywords: model mice; microglial cell; disease; pathology ... See more keywords
Inhibition of Autophagy In Vivo Extends Methamphetamine Toxicity to Mesencephalic Cell Bodies
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceuticals"
DOI: 10.3390/ph14101003
Abstract: Methamphetamine (METH) is a widely abused psychostimulant and a stress-inducing compound, which leads to neurotoxicity for nigrostriatal dopamine (DA) terminals in rodents and primates including humans. In vitro studies indicate that autophagy is a strong… read more here.
Keywords: cell bodies; toxicity; meth induced; autophagy ... See more keywords