Integrated process for scalable bioproduction of glycolic acid from cell catalysis of ethylene glycol.
Sign Up to like & getrecommendations! Published in 2018 at "Bioresource technology"
DOI: 10.1016/j.biortech.2018.08.021
Abstract: Glycolic acid (GA) is presently booming as a versatile raw material in the fields of high-grade cosmetics, polymer degradable materials, and drug production. The biocatalysis of ethylene glycol (EG) to GA is promising, with environmentally… read more here.
Keywords: glycolic acid; bioproduction; ethylene glycol; cell catalysis ... See more keywords
Efficient biosynthesis of high-value succinic acid and 5-hydroxyleucine using a multienzyme cascade and whole-cell catalysis.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b05529
Abstract: Succinic acid (SA), is applied in the food, chemical, and pharmaceutical industries. 5-Hydroxyleucine (5-HLeu) is a promising precursor for biosynthesis of antituberculosis drugs. Here, we designed a promising synthetic route for simultaneous production of SA… read more here.
Keywords: multienzyme cascade; succinic acid; whole cell; high value ... See more keywords
Cell Catalysis of Citrate to Itaconate by Engineered Halomonas bluephagenesis.
Sign Up to like & getrecommendations! Published in 2021 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00320
Abstract: Itaconic acid (IA), an important five-carbon unsaturated dicarboxylic acid, is one of the top 12 renewable chemicals with an urgent need to reduce industrial production costs. Halomonas bluephagenesis, which possesses the potential for cost-effective bioproduction… read more here.
Keywords: halomonas bluephagenesis; bluephagenesis; citrate; cell catalysis ... See more keywords
On-cell catalysis by surface engineering of live cells with an artificial metalloenzyme
Sign Up to like & getrecommendations! Published in 2018 at "Communications Chemistry"
DOI: 10.1038/s42004-018-0087-y
Abstract: Metal-catalyzed chemical transformations performed at the cellular level bear great potential for the manipulation of biological processes. The complexity of the cell renders the use of transition metal chemistry difficult in cellular systems. The delivery… read more here.
Keywords: artificial metalloenzyme; surface; chemistry; surface engineering ... See more keywords
Biosynthesis of 1,4-butanediol from erythritol using whole-cell catalysis
Sign Up to like & getrecommendations! Published in 2019 at "Biocatalysis and Biotransformation"
DOI: 10.1080/10242422.2018.1465414
Abstract: Abstract 1,4-Butanediol (BDO) biosynthesis from renewable resources is of increasing interest because of global energy and environmental problems. We have previously demonstrated the production of BDO from erythritol by whole-cell catalysis. Here, the effects of… read more here.
Keywords: butanediol; biosynthesis; whole cell; cell catalysis ... See more keywords
Rapid production of l‐DOPA by Vibrio natriegens, an emerging next‐generation whole‐cell catalysis chassis
Sign Up to like & getrecommendations! Published in 2022 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.14001
Abstract: 3, 4‐Dihydroxyphenyl‐l‐alanine (l‐DOPA) is a compound of high medical value and is considered effective as a treatment for Parkinson’s disease. Currently, bioproduction of l‐DOPA is mainly carried out by whole‐cell catalysis mediated by recombinant Escherichia… read more here.
Keywords: whole cell; production; cell catalysis; dopa ... See more keywords
Bioproduction of High-Concentration 4-Vinylguaiacol Using Whole-Cell Catalysis Harboring an Organic Solvent-Tolerant Phenolic Acid Decarboxylase From Bacillus atrophaeus
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.01798
Abstract: The compound 4-vinyl guaiacol (4-VG) is highly valued and widely applied in the pharmaceutical, cosmetic, and food industries. The bioproduction of 4-VG from ferulic acid (FA) by non-oxidative decarboxylation using phenolic acid decarboxylases is promising… read more here.
Keywords: whole cell; bacillus atrophaeus; acid decarboxylase; cell catalysis ... See more keywords