Chemotherapy and Inflammation Induced Damage of Intestinal Epithelium Is Associated with Increased T Cell Chemotaxis
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2019.12.025
Abstract: Gastro-intestinal (GI) Graft-versus-Host Disease (GvHD) involves a complex interplay of conditioning-related injury and the pathologic immune response at the epithelial level. Enhanced tissue damage is a risk factor for GVHD. We demonstrated that donor T… read more here.
Keywords: chemotherapy; epithelium; damage; gvhd ... See more keywords
CXCL10-armed oncolytic adenovirus promotes tumor-infiltrating T-cell chemotaxis to enhance anti-PD-1 therapy
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2118210
Abstract: ABSTRACT Resistance remains an obstacle to anti-programmed cell death protein 1 (PD-1) therapy in human cancer. One critical resistance mechanism is the lack of T cell chemotaxis in the tumor microenvironment (TME). CXCL10-CXCR3 signaling is… read more here.
Keywords: cell; cell chemotaxis; therapy; cxcl10 ... See more keywords
Peritoneal natural killer cell chemotaxis is decreased in women with pelvic endometriosis
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DOI: 10.1111/aji.13556
Abstract: NK cell and macrophage function are decreased in endometriosis, and the disease may involve reduced immune surveillance in the peritoneal cavity. NK cell cytotoxicity and migration ability (chemotaxis) are considered important; the former has been… read more here.
Keywords: cell; cell chemotaxis; peritoneal natural; natural killer ... See more keywords
ELMO2 association with Gαi2 regulates pancreatic cancer cell chemotaxis and metastasis
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DOI: 10.7717/peerj.8910
Abstract: Background Pancreatic cancer is a highly lethal disease. Nearly half of the patients have distant metastasis and remain asymptomatic. Emerging evidence suggests that the chemokine, CXCL12, has a role in cancer metastasis. The interaction between… read more here.
Keywords: pancreatic cancer; metastasis; cancer cell; cancer ... See more keywords