Host T-Cells Contribute to Immune Reconstitution and Improved Outcome in Recipients of CD34 Selected T-Cell Depleted Allografts (TCD HCT) with Full Hematopoietic Cell but Persistent Mixed T-Cell Chimerism
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2019.12.408
Abstract: Background Isolated mixed T-cell chimerism in otherwise fully engrafted recipients of TCDHCT has been associated, in some series, with risk of graft rejection or relapses and an indication for DLI. Thereto, we have analyzed the… read more here.
Keywords: mixed cell; chimerism; cell chimerism; host ... See more keywords
Mixed T cell CHIMERISM in bone marrow at day+30 after allogeneic stem cell transplantation: Correlation with acute GVHD grades III–IV and no impact on relapse and overall survival
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DOI: 10.1111/ejh.13772
Abstract: Early chimerism analysis is important to assess engraftment in allogeneic hematopoietic stem cell transplantations. read more here.
Keywords: mixed cell; cell; cell chimerism; stem cell ... See more keywords
Posttransplant MRD and T-cell chimerism status predict outcomes in patients allografted with AML/MDS.
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DOI: 10.1182/bloodadvances.2022009493
Abstract: Allogeneic stem-cell transplantation allows the delivery of curative graft-versus-leukemia (GVL) in patients with acute myeloid leukemia/myelodysplasia (AML/MDS). Surveillance of T-cell chimerism, measurable residual disease (MRD) and blast HLA-DR expression may inform whether GVL effectiveness is… read more here.
Keywords: aml mds; mrd; cell chimerism;