Immune Regulation by Dead Cell Clearance.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2015_472
Abstract: When cell death occurs in vivo, cell corpses are not left untreated, but are recognized and engulfed by phagocytes, such as macrophages and dendritic cells. In the past, cell death had been considered the final… read more here.
Keywords: dead cell; cell death; cell; cell clearance ... See more keywords
Rethinking Phagocytes: Clues from the Retina and Testes.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2018.01.004
Abstract: Specialized phagocytes are a newly appreciated classification of phagocyte that currently encompasses Sertoli cells (SCs) of the testes and the retinal pigment epithelial cells (RPE) of the retina. While these cells support very different tissues,… read more here.
Keywords: phagocytes clues; specialized phagocytes; rethinking phagocytes; clues retina ... See more keywords
Chemokines and phosphatidylserine: New binding partners for apoptotic cell clearance
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.943590
Abstract: Efferocytosis refers to efficient, non-inflammatory and immunologically silent elimination of dead and dying cells by phagocytes and is an essential and general process for maintaining homeostasis. Efferocytosis mechanisms are triggered by two main classes of… read more here.
Keywords: cell; find signals; efferocytosis; apoptotic cell ... See more keywords
Scrambled Eggs: Apoptotic Cell Clearance by Non-Professional Phagocytes in the Drosophila Ovary
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.01642
Abstract: For half of a century, it has been known that non-professional phagocytes, such as fibroblasts, endothelial, and epithelial cells, are capable of efferocytosis (engulfment of apoptotic cells). Non-professional phagocytes differ from professional phagocytes in the… read more here.
Keywords: drosophila ovary; cell clearance; non professional; professional phagocytes ... See more keywords
Potential Oncogenic Effect of the MERTK-Dependent Apoptotic-Cell Clearance Pathway in Starry-Sky B-Cell Lymphoma
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01759
Abstract: The histological architecture of certain aggressive B-cell lymphomas (prototypically Burkitt's lymphoma, BL) is characterized by a “starry-sky” (SS) appearance. This is caused by tumor-associated macrophages (TAMs), which appear in standard histological preparations as “stars” in… read more here.
Keywords: apoptotic cell; starry sky; cell; cell clearance ... See more keywords
trim-21 promotes proteasomal degradation of CED-1 for apoptotic cell clearance in C. elegans
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.76436
Abstract: The phagocytic receptor CED-1 mediates apoptotic cell recognition by phagocytic cells, enabling cell corpse clearance in Caenorhabditis elegans. Whether appropriate levels of CED-1 are maintained for executing the engulfment function remains unknown. Here, we identified… read more here.
Keywords: apoptotic cell; cell; proteasomal degradation; cell clearance ... See more keywords