Telomere-length dependent T-cell clonal expansion: A model linking ageing to COVID-19 T-cell lymphopenia and mortality
Sign Up to like & getrecommendations! Published in 2022 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2022.103978
Abstract: Background Severe COVID-19 T-cell lymphopenia is more common among older adults and entails poor prognosis. Offsetting the decline in T-cell count during COVID-19 demands fast and massive T-cell clonal expansion, which is telomere length (TL)-dependent.… read more here.
Keywords: cell clonal; covid cell; clonal expansion; cell ... See more keywords
Glioblastoma Stem Cell Clonal Dynamics Drive Intratumor Heterogeneity.
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DOI: 10.1158/2159-8290.cd-rw2017-172
Abstract: GBM heterogeneity is primarily driven by the stochastic outcome of GBM stem cell hierarchical growth. read more here.
Keywords: heterogeneity; stem cell; glioblastoma stem; clonal dynamics ... See more keywords