Articles with "cell clusters" as a keyword



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Clinical significance of CD8-positive lymphocytes on tumor cell clusters of ascites cell block in ovarian high-grade serous carcinoma.

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Published in 2022 at "Cancer medicine"

DOI: 10.1002/cam4.4592

Abstract: BACKGROUND The clinical significance of CD8-positive (CD8+ ) lymphocytes on tumor cell clusters of ascites cell blocks in patients with ovarian high-grade serous carcinoma (HGSC) was investigated. METHODS Among HGSC patients who underwent surgery from… read more here.

Keywords: group; cd8; cd8 lymphocytes; cell ... See more keywords
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Prognostic significance of the presence of epithelial cell clusters in the ascites of patients with pseudomyxoma peritonei

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Published in 2019 at "Diagnostic Cytopathology"

DOI: 10.1002/dc.24262

Abstract: Pseudomyxoma peritonei (PMP) is a rare condition characterized by intraperitoneal accumulation of mucus due to mucinous neoplasia. The characteristic cytological feature of PMP in the ascites is abundant mucus with or without epithelial cell clusters.… read more here.

Keywords: epithelial cell; cell clusters; prognostic significance; pseudomyxoma peritonei ... See more keywords
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Clear cell clusters in the kidney: a rare finding that should not be misdiagnosed as renal cell carcinoma

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Published in 2021 at "Virchows Archiv"

DOI: 10.1007/s00428-021-03018-4

Abstract: Clear cytoplasm is a major characteristic feature of most malignant renal neoplasms. Benign clear cells in the renal parenchyma, usually histiocytes, can occasionally be found, but they are infrequently of an epithelial nature. We report… read more here.

Keywords: clusters kidney; renal cell; cell clusters; clear cell ... See more keywords
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To lead or to herd: optimal strategies for 3D collective migration of cell clusters.

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Published in 2020 at "Biomechanics and modeling in mechanobiology"

DOI: 10.1007/s10237-020-01290-y

Abstract: Cells migrating in clusters play a significant role in a number of biological processes such as embryogenesis, wound healing, and tumor metastasis during cancer progression. A variety of environmental and biochemical factors can influence the… read more here.

Keywords: cell clusters; cell migration; migration; collective migration ... See more keywords
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Single-cell EMT-related transcriptional analysis revealed intra-cluster heterogeneity of tumor cell clusters in epithelial ovarian cancer ascites

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Published in 2020 at "Oncogene"

DOI: 10.1038/s41388-020-1288-2

Abstract: Malignant ascites of epithelial ovarian cancer is a metastatic tumor microenvironment in which large amounts of disseminated single cells (DSCs) and disseminated tumor cell clusters (DTCCs) are commonly observed. The tumor cell clusters are known… read more here.

Keywords: cell clusters; analysis; tumor cell; cancer ... See more keywords
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Genomic alterations and evolution of cell clusters in metastatic invasive micropapillary carcinoma of the breast

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Published in 2022 at "Nature Communications"

DOI: 10.1038/s41467-021-27794-4

Abstract: Invasive micropapillary carcinoma (IMPC) has very high rates of lymphovascular invasion and lymph node metastasis and has been reported in several organs. However, the genomic mechanisms underlying its metastasis are unclear. Here, we perform whole-genome… read more here.

Keywords: micropapillary carcinoma; lymph node; invasive micropapillary; cell clusters ... See more keywords
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Graph analysis of cell clusters forming vascular networks

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Published in 2018 at "Royal Society Open Science"

DOI: 10.1098/rsos.171592

Abstract: This manuscript describes the experimental observation of vasculogenesis in chick embryos by means of network analysis. The formation of the vascular network was observed in the area opaca of embryos from 40 to 55 h of… read more here.

Keywords: vascular networks; cell clusters; network; vascular network ... See more keywords
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Algorithm to identify circulating tumor cell clusters using in vivo flow cytometer

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Published in 2018 at "Journal of Innovative Optical Health Sciences"

DOI: 10.1142/s1793545818500244

Abstract: Recent studies in oncology have addressed the importance of detecting circulating tumor cell clusters because circulating tumor cell clusters might survive and metastasize more easily than single c... read more here.

Keywords: tumor cell; circulating tumor; cell clusters; algorithm identify ... See more keywords
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The Prognostic Model Established by the Differential Expression Genes Based on CD8+ T Cells to Evaluate the Prognosis and the Response to Immunotherapy in Osteosarcoma

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Published in 2023 at "Mediators of Inflammation"

DOI: 10.1155/2023/6563609

Abstract: Osteosarcoma (OS) is a malignant tumor with an extremely poor prognosis, especially in progressive patients. Immunotherapy based on immune checkpoint inhibitors (ICIs) is considered to be a promising treatment option for OS. Due to tumor… read more here.

Keywords: cell; prognosis; immunotherapy; cell clusters ... See more keywords
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Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML

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Published in 2020 at "Blood"

DOI: 10.1182/blood-2020-142513

Abstract: Introduction: While advances in front-line conventional chemotherapy have increased the likelihood of attaining remission in pediatric AML, relapse rates remain high (25-35%), and novel therapies are needed (Zhang, Savage et al. 2019). The clinical and… read more here.

Keywords: blast; cell clusters; analysis; remission ... See more keywords
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CIPR: a web-based R/shiny app and R package to annotate cell clusters in single cell RNA sequencing experiments

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Published in 2020 at "BMC Bioinformatics"

DOI: 10.1186/s12859-020-3538-2

Abstract: Background Single cell RNA sequencing (scRNAseq) has provided invaluable insights into cellular heterogeneity and functional states in health and disease. During the analysis of scRNAseq data, annotating the biological identity of cell clusters is an… read more here.

Keywords: single cell; cell clusters; cell rna; rna sequencing ... See more keywords