Effect of a Synthetic Organoselenium Compound on Post-Vaccination Immunopoiesis in the Red Bone Marrow and Cell Composition of Peripheral Blood of White Mice Vaccinated with Yersinia pestis EV.
Sign Up to like & getrecommendations! Published in 2021 at "Bulletin of experimental biology and medicine"
DOI: 10.1007/s10517-021-05287-0
Abstract: We studied the effect of an experimental synthetic organoselenium compound 2,6-dipyridinium- 9-selenabicyclo[3.3.1]nonane dibromide (974zh) on the cell composition of the red bone marrow and peripheral blood in white mice. The study drug co-administered with Yersinia… read more here.
Keywords: synthetic organoselenium; cell composition; bone; organoselenium compound ... See more keywords
Cell composition analysis of bulk genomics using single cell data
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DOI: 10.1038/s41592-019-0355-5
Abstract: Single-cell RNA sequencing (scRNA-seq) is a rich resource of cellular heterogeneity, opening new avenues in the study of complex tissues. We introduce Cell Population Mapping (CPM), a deconvolution algorithm in which reference scRNA-seq profiles are… read more here.
Keywords: single cell; cell; composition analysis; cell composition ... See more keywords
Diet induced changes in the microbiota and cell composition of rabbit gut associated lymphoid tissue (GALT)
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DOI: 10.1038/s41598-018-32484-1
Abstract: The gut associated lymphoid tissue (GALT) is the largest immune organ of the body. Although the gut transient and mucosa-associated microbiota have been largely studied, the microbiota that colonizes the GALT has received less attention.… read more here.
Keywords: gut; lymphoid tissue; cell composition; cell ... See more keywords
The effect of smoking on chronic inflammation, immune function and blood cell composition
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DOI: 10.1038/s41598-020-76556-7
Abstract: Smoking is the number one risk factor for cancer mortality but only 15–20% of heavy smokers develop lung cancer. It would, therefore, be of great benefit to identify those at high risk early on so… read more here.
Keywords: significantly higher; blood; blood cell; cell composition ... See more keywords
Inference of immune cell composition on the expression profiles of mouse tissue
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DOI: 10.1038/srep40508
Abstract: Mice are some of the widely used experimental animal models for studying human diseases. Defining the compositions of immune cell populations in various tissues from experimental mouse models is critical to understanding the involvement of… read more here.
Keywords: immune cell; cell composition; expression; immucc ... See more keywords
Primary culture of mouse embryonic spinal cord neurons: cell composition and suitability for axonal regeneration studies
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DOI: 10.1080/00207454.2019.1567508
Abstract: Abstract Objective: Primary culture is an effective experimental model to study molecular mechanisms that drive axonal regeneration after central nervous system injury. However, the culture of spinal cord (SC) cells remains poorly characterized. Here, we… read more here.
Keywords: cell composition; axonal regeneration; culture mouse; culture ... See more keywords
The role of blood cell composition in epidemiologic studies of telomeres.
Sign Up to like & getrecommendations! Published in 2020 at "Epidemiology"
DOI: 10.1097/ede.0000000000001187
Abstract: REFERENCES 1. VanderWeele TJ, Luedtke AR, van der Laan MJ, Kessler RC. Selecting optimal subgroups for treatment using many covariates. Epidemiology. 2019;300:334–341. 2. Korte B, Vygen J. Combinatorial Optimization: Theory and Algorithms. 4th ed. Heidelberg:… read more here.
Keywords: epidemiologic studies; role blood; blood cell; composition epidemiologic ... See more keywords
Cell composition inference and identification of layer-specific spatial transcriptional profiles with POLARIS
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DOI: 10.1126/sciadv.add9818
Abstract: Spatial transcriptomics (ST) technology, providing spatially resolved transcriptional profiles, facilitates advanced understanding of key biological processes related to health and disease. Sequencing-based ST technologies provide whole-transcriptome profiles but are limited by the non–single cell–level resolution.… read more here.
Keywords: cell; composition inference; composition; layer ... See more keywords
TOAST: improving reference-free cell composition estimation by cross-cell type differential analysis
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DOI: 10.1186/s13059-019-1778-0
Abstract: In the analysis of high-throughput data from complex samples, cell composition is an important factor that needs to be accounted for. Except for a limited number of tissues with known pure cell type profiles, a… read more here.
Keywords: composition estimation; cell composition; composition; reference free ... See more keywords
ImmuCellDB: An Indicative Database of Immune Cell Composition From Different Tissues and Disease Conditions in Mouse and Human
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.670070
Abstract: Immune cell composition is highly divergent across different tissues and diseases. A comprehensive resource of tissue immune cells across different conditions in mouse and human will thus provide great understanding of the immune microenvironment of… read more here.
Keywords: immune; immune cell; tissue; cell composition ... See more keywords
B Cell Composition Is Altered After Kidney Transplantation and Transitional B Cells Correlate With SARS-CoV-2 Vaccination Response
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.818882
Abstract: Background The COVID-19 pandemic has major implications on kidney transplant recipients (KTRs) since they show increased mortality due to impaired immune responses to SARS-CoV-2 infection and a reduced efficacy of SARS-CoV-2 vaccination. Surprisingly, dialysis patients… read more here.
Keywords: vaccination; bcs; kidney transplantation; cov vaccination ... See more keywords