A novel integrated biomarker index for the assessment of hematological responses in MPNs during treatment with hydroxyurea and interferon‐alpha2
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5285
Abstract: Conventional cytoreductive therapy for patients with chronic Philadelphia‐negative myeloproliferative neoplasms (MPNs) includes hydroxyurea (HU), interferon‐alpha2 (IFN), and anagrelide. HU is worldwide the most used cytoreductive agent, which lowers elevated blood cell counts within days in… read more here.
Keywords: cell counts; cell; hydroxyurea interferon; interferon alpha2 ... See more keywords
Bone Density Loss Is Associated With Blood Cell Counts
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3000
Abstract: Hematopoiesis depends on a supportive microenvironment. Preclinical studies in mice have demonstrated that osteoblasts influence the development of blood cells, particularly erythrocytes, B lymphocytes, and neutrophils. However, it is unknown whether osteoblast numbers or function… read more here.
Keywords: cell counts; bmd loss; blood; blood cell ... See more keywords
T cell counts and IL‐6 concentration in blood of North African COVID‐19 patients are two independent prognostic factors for severe disease and death
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4cova1020-703r
Abstract: The immune system plays a crucial role in the response against severe acute respiratory syndrome coronavirus 2 with significant differences among patients. The study investigated the relationships between lymphocyte subsets, cytokines, and disease outcomes in… read more here.
Keywords: blood; severe disease; covid patients; cell counts ... See more keywords
Nomogram for prediction of long-term survival with hepatocellular carcinoma based on NK cell counts.
Sign Up to like & getrecommendations! Published in 2022 at "Annals of hepatology"
DOI: 10.1016/j.aohep.2022.100672
Abstract: INTRODUCTION Among all immune cells, natural killer (NK) cells play an important role as the first line of defense against tumor. The purpose of our study is to observe whether the NK cell counts can… read more here.
Keywords: survival; hcc; cell counts; year ... See more keywords
Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical immunology"
DOI: 10.1016/j.clim.2018.03.002
Abstract: This study evaluated the short-term effects of tofacitinib treatment on peripheral blood leukocyte phenotype and function, and the reversibility of any such effects following treatment withdrawal in healthy volunteers. Cytomegalovirus (CMV)-seropositive subjects received oral tofacitinib… read more here.
Keywords: tofacitinib treatment; cell counts; blood; withdrawal ... See more keywords
Impact of spiking techniques on the survival of Staphylococcus aureus in artificially contaminated condiments
Sign Up to like & getrecommendations! Published in 2017 at "Food Control"
DOI: 10.1016/j.foodcont.2016.10.021
Abstract: Abstract Tenacity studies are of relevance for microbial food safety risk assessment. Investigations on the survival of microorganisms in food matrices often require an artificial contamination step prior to microbial testing. Artificial contamination of low-moisture… read more here.
Keywords: technique; spiking techniques; aureus; techniques survival ... See more keywords
Increased IL-8 levels in HIV-infected individuals who initiated ART with CD4+ T cell counts
Sign Up to like & getrecommendations! Published in 2020 at "Microbes and infection"
DOI: 10.1016/j.micinf.2020.05.019
Abstract: The identification of inflammatory markers in HIV+ individuals on ART is fundamental since chronic ART-controlled HIV infection is linked to an increased inflammatory state. In this context, we assessed plasma levels of pro-inflammatory cytokines (IL-1β,… read more here.
Keywords: individuals initiated; inflammation; cell counts; hiv individuals ... See more keywords
Differential cell counts using center-point networks achieves human-level accuracy and efficiency over segmentation
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DOI: 10.1038/s41598-021-96067-3
Abstract: Differential cell counts is a challenging task when applying computer vision algorithms to pathology. Existing approaches to train cell recognition require high availability of multi-class segmentation and/or bounding box annotations and suffer in performance when… read more here.
Keywords: segmentation; cell counts; pathology; point ... See more keywords
The Imbalance Between Intestinal Th17 and Treg Cells Is Associated with an Incomplete Immune Reconstitution During Long-Term Antiretroviral Therapy in Patients with HIV.
Sign Up to like & getrecommendations! Published in 2023 at "Viral immunology"
DOI: 10.1089/vim.2023.0017
Abstract: Studies assessing the gut mucosal immune balance in HIV-infected patients using intestinal samples are scarce. In this study, we used intestinal mucosal specimens from the ileocecal region of seven immunological nonresponders (INRs), nine immunological responders… read more here.
Keywords: treg; th17 treg; treg ratio; th17 ... See more keywords
Predictors of Rituximab Effect on Modified Rodnan Skin Score in Systemic Sclerosis: a machine learning analysis of the DESIRES trial.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac023
Abstract: OBJECTIVES The DESIRES trial showed that rituximab is effective in treating skin sclerosis in systemic sclerosis. However, which patient groups are likely to benefit from rituximab is unknown. METHODS We performed post-hoc analysis on prospective… read more here.
Keywords: cd19 positive; sclerosis; trial; cell counts ... See more keywords
Association between serum amylase levels and CD4 cell counts in newly diagnosed people living with HIV: A case-control study
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000032638
Abstract: Serum amylase is a direct reflection of pancreatic injury. Several clinical studies have indicated that antiretroviral therapy may be the main cause of increased serum amylase in people living with human immunodeficiency virus (PLWH). However,… read more here.
Keywords: cd4 cell; cell counts; serum amylase; amylase ... See more keywords