Leucine rich repeats and calponin homology domain containing 1 inhibits NK-92 cell cytotoxicity through attenuating Src signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Immunobiology"
DOI: 10.1016/j.imbio.2020.151934
Abstract: NK-92 cell line has been used as anti-tumor cytotoxic effector cells in immunotherapy. Leucine-rich repeats and calponin homology domain containing 1 (LRCH1) is a novel gene of which the function is unclear. In the present… read more here.
Keywords: tumor; cytotoxicity; cell cytotoxicity; lrch1 knockout ... See more keywords
Comparative mammalian cell cytotoxicity of wastewater with elevated bromide and iodide after chlorination, chloramination, or ozonation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of environmental sciences"
DOI: 10.1016/j.jes.2017.03.030
Abstract: Recycling wastewater is becoming more common as communities around the world try to better control their water resources against an increased frequency of either prolonged droughts or intense flooding. For communities in coastal areas, wastewaters… read more here.
Keywords: chlorination; mammalian cell; cell cytotoxicity; wastewater ... See more keywords
Thiol Reactivity Analyses To Predict Mammalian Cell Cytotoxicity of Water Samples.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental science & technology"
DOI: 10.1021/acs.est.8b01675
Abstract: An in chemico high throughput assay based on N-acetylcysteine was developed and used in conjunction with previous and new mammalian cell cytotoxicity data. Our objective was to derive an empirical equation with confidence levels for… read more here.
Keywords: mammalian cell; water samples; cell cytotoxicity;
Expression of KIR2DS1 does not significantly contribute to NK cell cytotoxicity in HLA-C1/C2 heterozygous haplotype B donors
Sign Up to like & getrecommendations! Published in 2017 at "International Immunology"
DOI: 10.1093/intimm/dxx052
Abstract: NK cells are functionally controlled by the killer immunoglobulin-like receptor (KIR) family that comprises inhibitory (iKIR) and activating (aKIR) members. Genetic association studies suggest that donors expressing aKIRs next to iKIRs will be superior donors… read more here.
Keywords: haplotype donors; cell cytotoxicity; significantly contribute; haplotype ... See more keywords
Detection of Free Toxin B in the Stool of Asymptomatic Clostridioides difficile Carriers by the Cell Cytotoxicity Neutralization Assay
Sign Up to like & getrecommendations! Published in 2021 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofab209
Abstract: Abstract Cell cytotoxicity neutralization assay (CCNA) is considered to be a gold standard to diagnose Clostridioides difficile infections. We performed CCNA on 77 consecutive admission screening rectal swabs from asymptomatic toxigenic C. difficile carriers. Thirty-nine… read more here.
Keywords: neutralization assay; clostridioides difficile; cell cytotoxicity; cytotoxicity neutralization ... See more keywords
Abstract 911: Butyrophilin 3A2 expression plays a critical role in phosphoantigen-mediated γδ T cell cytotoxicity of neuroblastoma cells
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-911
Abstract: The clinical use of antibodies targeting the diaslganglioside GD2 improved survival and clearly identified a role for immunotherapy in the aggressive pediatric solid tumor neuroblastoma (NB). Even so, the 5-year survival rate for high risk… read more here.
Keywords: cell; role; bt3; cell cytotoxicity ... See more keywords
Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control.
Sign Up to like & getrecommendations! Published in 2017 at "JCI insight"
DOI: 10.1172/jci.insight.95128
Abstract: NK cell activation has been shown to be metabolically regulated in vitro; however, the role of metabolism during in vivo NK cell responses to infection is unknown. We examined the role of glycolysis in NK… read more here.
Keywords: metabolism; infection; cell cytotoxicity; cytomegalovirus ... See more keywords
Functional and genetic testing in adults with HLH reveals an inflammatory profile rather than a cytotoxicity defect
Sign Up to like & getrecommendations! Published in 2020 at "Blood"
DOI: 10.1182/blood.2019003664
Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory condition. Primary HLH occurs early in life as a result of monogenic biallelic mutations affecting lymphocyte cytotoxicity. Secondary HLH occurs mostly in adults secondary to infection, lymphoma, or… read more here.
Keywords: cell cytotoxicity; cytotoxicity; secondary hlh; lymphocyte cytotoxicity ... See more keywords
Effect of dendritic cells (DC) transduced with chimeric antigen receptor (CAR) on CAR T-cell cytotoxicity.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.7_suppl.144
Abstract: 144Background: T cells interacting DC could be superior in T cell cytotoxicity. CD141+/Cleg9a+ intra-tumoral DC play a critical role in tumor cytotoxicity. Therefore, combining intra-tumoral DC in CAR T cell would safely increase localized CAR… read more here.
Keywords: car cell; cell cytotoxicity; car car; cell ... See more keywords
Korean mistletoe lectin enhances natural killer cell cytotoxicity via upregulation of perforin expression.
Sign Up to like & getrecommendations! Published in 2018 at "Asian Pacific journal of allergy and immunology"
DOI: 10.12932/ap-030417-0067
Abstract: BACKGROUND Natural killer (NK) cells are crucial components of the innate immune system, providing the first line of defense against pathogens. In a previous study, we demonstrated prophylactic activity of water extract of Korean mistletoe… read more here.
Keywords: cell; cell cytotoxicity; korean mistletoe; expression ... See more keywords
MiR-506 Promotes Natural Killer Cell Cytotoxicity against Human Hepatocellular Carcinoma Cells by Targeting STAT3
Sign Up to like & getrecommendations! Published in 2019 at "Yonsei Medical Journal"
DOI: 10.3349/ymj.2019.60.1.22
Abstract: Purpose It is well documented that natural killer (NK) cytotoxicity against hepatocellular carcinoma (HCC) cells is impaired in HCC, which might account for the failure of anti-tumor immune response. miRNAs are considered as important regulators… read more here.
Keywords: hcc; mir 506; stat3; cell cytotoxicity ... See more keywords