An ultra scale‐down methodology to characterize aspects of the response of human cells to processing by membrane separation operations
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26257
Abstract: Tools that allow cost‐effective screening of the susceptibility of cell lines to operating conditions which may apply during full scale processing are central to the rapid development of robust processes for cell‐based therapies. In this… read more here.
Keywords: methodology; cell damage; ultra scale; response human ... See more keywords
Quercetin, but not rutin, attenuated hydrogen peroxide-induced cell damage via heme oxygenase-1 induction in endothelial cells.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.108157
Abstract: Oxidative stress plays an important role in the pathogenesis of cardiovascular disease. Quercetin, a naturally occurring flavonoid presents in plants and human diet, has been reported to exert antioxidant properties in vivo and in vitro.… read more here.
Keywords: hmox1; endothelial cells; quercetin; cell ... See more keywords
Evaluation of cell damage induced by irradiated Zinc-Phthalocyanine-gold dendrimeric nanoparticles in a breast cancer cell line
Sign Up to like & getrecommendations! Published in 2018 at "Biomedical Journal"
DOI: 10.1016/j.bj.2018.05.002
Abstract: Background Cancer is a non-communicable disease that occurs following a mutation in the genes which control cell growth. Breast cancer is the most diagnosed cancer among South African women and a major cause of cancer-related… read more here.
Keywords: cell line; breast cancer; cancer cell; cancer ... See more keywords
Carvedilol prevents pancreatic β-cell damage and the development of type 1 diabetes in mice by the inhibition of proinflammatory cytokines, NF-κB, COX-2, iNOS and oxidative stress.
Sign Up to like & getrecommendations! Published in 2020 at "Cytokine"
DOI: 10.1016/j.cyto.2020.155394
Abstract: Inflammation is one of the main mechanisms of pancreatic β-cell damage and the development of type 1 diabetes (T1D). Carvedilol, a beta-adrenergic receptor blocker, has been demonstrated to have anti-inflammatory and antioxidant effects. The aim… read more here.
Keywords: damage development; pancreatic cell; carvedilol; cell damage ... See more keywords
New evidences for a role of mGluR7 in astrocyte survival: Possible implications for neuroprotection
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.08.035
Abstract: ABSTRACT A specific activation of metabotropic glutamate receptor 7 (mGluR7) has been shown to be neuroprotective in various models of neuronal cell damage, however, its role in glia cell survival has not been studied, yet.… read more here.
Keywords: glia cell; cell; cell damage; mglur7 ... See more keywords
Influence of antibacterial effects of tetracycline, laser, and photodynamic therapy on cell viability, cell damage, and virulence of Porphyromonas gingivalis.
Sign Up to like & getrecommendations! Published in 2021 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2021.102617
Abstract: INTRODUCTION This study compares and evaluates the efficacy tetracycline, laser and photodynamic therapy on bacterial counts, cell damage, cell viability and neutralization of gingipains. MATERIAL AND METHODS P.gingivalis (ATCC 33277) was cultured anaerobically. The minimal… read more here.
Keywords: cell viability; photodynamic therapy; tetracycline laser; cell ... See more keywords
Melatonin Ameliorates Cisplatin-Induced Renal Tubular Epithelial Cell Damage through PPARα/FAO Regulation.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.2c00121
Abstract: Previous studies revealed that melatonin ameliorated acute renal injury induced by cisplatin, but the mechanisms remain unclear. Peroxidase proliferative receptor α (PPARα) is considered the major regulator of fatty acid oxidation (FAO), which is an… read more here.
Keywords: cell; cell damage; cisplatin induced; ppar ... See more keywords
Lycopene prevents DEHP-induced Leydig cell damage with the Nrf2 antioxidant signaling pathway in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b06882
Abstract: As a plasticizer, di(2-ethylhexyl) phthalate (DEHP) is the most usually used phthalates. Leydig cell is a male-specific cell, which plays a principal role in spermatogenesis and masculinization by androgens of synthesis and secretion. Numerous researchers… read more here.
Keywords: leydig cell; dehp induced; cell; cell damage ... See more keywords
Cationic Organochalcogen with Monomer/Excimer Emissions for Dual-Color Live Cell Imaging and Cell Damage Diagnosis.
Sign Up to like & getrecommendations! Published in 2018 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b12521
Abstract: Studies on the development of fluorescent organic molecules with different emission colors for imaging of organelles and their biomedical application are gaining lots of focus recently. Here, we report two cationic organochalcogens 1 and 2,… read more here.
Keywords: dual color; cell; cell damage; emission ... See more keywords
Chemical Modifications Reduce Auditory Cell Damage Induced by Aminoglycoside Antibiotics.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b12420
Abstract: Although aminoglycoside antibiotics are effective against Gram-negative infections, these drugs often cause irreversible hearing damage. Binding to the decoding site of eukaryotic ribosomes appears to result in ototoxicity, but there is evidence that other effects… read more here.
Keywords: aminoglycoside antibiotics; reduce auditory; chemical modifications; auditory cell ... See more keywords
Streptozotocin-induced β-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-29434-2
Abstract: Diabetes mellitus is a group of disorders characterized by prolonged high levels of circulating blood glucose. Type 1 diabetes is caused by decreased insulin production in the pancreas whereas type 2 diabetes may develop due… read more here.
Keywords: insulin; streptozotocin induced; damage high; brain ... See more keywords