Paneth cell α-defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments
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DOI: 10.1073/pnas.1817376116
Abstract: Significance Paneth cells provide intestinal host defense against pathogens and control the healthy microbiota by secreting antimicrobial peptides. We show that the most abundant secreted Paneth cell products, human defensin HD-5 and HD-6, show a… read more here.
Keywords: degradation; paneth cell; host; antimicrobial peptides ... See more keywords