Autologous transplantation of conjunctiva by modifying simple limbal epithelial transplantation for limbal stem cell deficiency
Sign Up to like & getrecommendations! Published in 2019 at "Japanese Journal of Ophthalmology"
DOI: 10.1007/s10384-019-00701-7
Abstract: Purpose As a treatment to replace regenerative medicine to treat limbal stem cell deficiency (LSCD), we performed 4 consecutive cases of autologous transplantation of conjunctival explants by modifying simple limbal epithelial transplantation (SLET). Study design… read more here.
Keywords: limbal stem; stem cell; transplantation; autologous transplantation ... See more keywords
Azathioprine-Associated Complete NK Cell Deficiency
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Immunology"
DOI: 10.1007/s10875-017-0414-6
Abstract: To the editor, We report the case of a 5-year-old Caucasian girl with very early-onset inflammatory bowel disease (VOIBD) who had inadequate response to initial therapy with azathioprine. Immune system evaluation revealed an isolated complete… read more here.
Keywords: azathioprine associated; azathioprine; disease; cell deficiency ... See more keywords
Identification of 22 novel BTK gene variants in B cell deficiency with hypogammaglobulinemia.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108788
Abstract: X-linked agammaglobulinemia (XLA) is an inborn error of immunity caused by pathogenic variants in the BTK gene, resulting in impaired B cell differentiation and maturation. Over 900 variants have already been described in this gene,… read more here.
Keywords: novel; btk gene; cell deficiency; variants btk ... See more keywords
Diagnosis and management of limbal stem cell deficiency, challenges, and future prospects
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Ophthalmology"
DOI: 10.1080/17469899.2021.1933441
Abstract: ABSTRACT Introduction: Corneal limbal stem cell deficiency is a multifaceted, sight-threatening disease process that can be challenging to diagnose and treat. Areas covered: This review discusses normal corneal limbal stem cell health, causes and diagnosis… read more here.
Keywords: limbal stem; cell deficiency; stem cell;
Current and Emerging Therapies for Limbal Stem Cell Deficiency
Sign Up to like & getrecommendations! Published in 2022 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szab028
Abstract: Abstract The corneal epithelium serves to protect the underlying cornea from the external environment and is essential for corneal transparency and optimal visual function. Regeneration of this epithelium is dependent on a population of stem… read more here.
Keywords: stem; cell deficiency; stem cell; limbal stem ... See more keywords
Other Causes of Limbal Stem Cell Deficiency.
Sign Up to like & getrecommendations! Published in 2019 at "Cornea"
DOI: 10.1097/ico.0000000000002136
Abstract: To the Editor: We read with great interest the article entitled “Global Consensus on Definition, Classification, Diagnosis, and Staging of Limbal Stem Cell Deficiency” by Deng et al.1 We consider this global consensus very helpful… read more here.
Keywords: cell deficiency; stem cell; limbal stem; deficiency ... See more keywords
Cytokeratin 13 Is a New Biomarker for the Diagnosis of Limbal Stem Cell Deficiency.
Sign Up to like & getrecommendations! Published in 2021 at "Cornea"
DOI: 10.1097/ico.0000000000002903
Abstract: PURPOSE The purpose of this study was to evaluate the expression of cytokeratin (K) 13 on the corneal surface and to validate its application in the diagnosis of limbal stem cell deficiency (LSCD). METHODS This… read more here.
Keywords: diagnosis limbal; stem cell; k13 cells; cell deficiency ... See more keywords
Complete B Cell Deficiency Reduces Allograft Inflammation and Intragraft Macrophages in a Rat Kidney Transplant Model
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation"
DOI: 10.1097/tp.0000000000002010
Abstract: Background Increasingly, it is being appreciated that B cells have broad roles beyond the humoral response and are able to contribute to and regulate inflammation. The specific role of B cells in the pathogenesis of… read more here.
Keywords: inflammation; model; cell deficiency; cell ... See more keywords
Мodification of Mechanical Limbal Stem Cell Deficiency Model
Sign Up to like & getrecommendations! Published in 2018 at "Test"
DOI: 10.18008/1816-5095-2018-1-51-57
Abstract: Introduction. Ocular surface diseases related with limbal epithelial stem cells dysfunction were united in term “limbal stem cell deficiency” (LSCD). For experimental study of the regenerative processes and evaluation of the success of new LSCD… read more here.
Keywords: limbal stem; model; stem cell; cell deficiency ... See more keywords
Surgical Management of Bilateral Limbal Stem Cell Deficiency.
Sign Up to like & getrecommendations! Published in 2023 at "Acta medica portuguesa"
DOI: 10.20344/amp.18960
Abstract: At the age of 43 years-old, a man was left with bilateral limbal stem cell deficiency after an ocular alkaline burn with lime, which resulted in corneal opacification. After multiple unsuccessful surgical attempts to restore… read more here.
Keywords: limbal stem; stem cell; bilateral limbal; stem ... See more keywords
Riboflavin Attenuates Influenza Virus Through Cytokine-Mediated Effects on the Diversity of the Gut Microbiota in MAIT Cell Deficiency Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.916580
Abstract: Influenza is a serious respiratory disease that continues to threaten global health. Mucosa-associated invariant T (MAIT) cells use T-cell receptors (TCRs) that recognize microbial riboflavin derived intermediates presented by the major histocompatibility complex (MHC) class… read more here.
Keywords: cell; riboflavin; mait; mice ... See more keywords