Polymers and Nanostructured Materials for Drug Nanoparticles, Bioimaging, and Cell Delivery
Sign Up to like & getrecommendations! Published in 2020 at "Materials Science and Technology"
DOI: 10.1002/9783527603978.mst0483
Abstract: Polymers can be designed, synthesized, and modified for a wide range of applications. The use of biopolymers and nanostructured materials (either made of polymers or fabricated with polymers) have been extensively investigated for biomedical and… read more here.
Keywords: cell delivery; cell; nanostructured materials; drug nanoparticles ... See more keywords
Gelatin Methacryloyl Based Injectable Cryogels With Tunable Degradability For Cell Delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200562
Abstract: Scaffold-based cell delivery can improve therapeutic effects of transplanted cells in cell therapy. A biomaterial scaffold serves as a niche for cell growth and proliferation which improves cell survival and overall function post cell delivery.… read more here.
Keywords: cell; based injectable; degradability; gelatin methacryloyl ... See more keywords
Magnetic Microsphere Scaffold-Based Soft Microbots for Targeted Mesenchymal Stem Cell Delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202300430
Abstract: A soft microbot assembled from individual magnetic microsphere scaffold (MMS) beads carrying mesenchymal stem cells (MSC) is navigated under magnetic actuation, where an oscillating field induces mechanical flexion to propel the microbot toward the target… read more here.
Keywords: magnetic microsphere; stem cell; cell delivery; microsphere scaffold ... See more keywords
Bioactive in situ crosslinkable polymer-peptide hydrogel for cell delivery to the intervertebral disc in a rat model.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.06.045
Abstract: Degeneration of the intervertebral disc (IVD) is associated with significant biochemical and morphological changes that include a loss of disc height, decreased water content and decreased cellularity. Cell delivery has been widely explored as a… read more here.
Keywords: hydrogel; cell delivery; intervertebral disc; cell ... See more keywords
An injectable chitosan/dextran/β -glycerophosphate hydrogel as cell delivery carrier for therapy of myocardial infarction.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2019.115516
Abstract: Acute myocardial infarction (MI) is a common cardiovascular disease with high mortality. In this study, an injectable thermosensitive hydrogel of chitosan (CS)/dextran (DEX)/β-glycerophosphate (β-GP) loaded with umbilical cord mesenchymal stem cells (UCMSCs) was prepared for… read more here.
Keywords: chitosan dextran; cell delivery; myocardial infarction; hydrogel ... See more keywords
Biodegradable microrobots for targeting cell delivery.
Sign Up to like & getrecommendations! Published in 2017 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2017.02.015
Abstract: These days, cell delivery is considered a potential method for treatment of many genetic diseases or tissue regeneration applications. In conventional cell delivery methods, cells are encapsulated in or cultured on biocompatible polymers. However, the… read more here.
Keywords: microrobots targeting; targeting cell; delivery; cell delivery ... See more keywords
Defining the optimal historical control group for a phase 1 trial of mesenchymal stromal cell delivery through cardiopulmonary bypass in neonates and infants.
Sign Up to like & getrecommendations! Published in 2022 at "Cardiology in the young"
DOI: 10.1017/s1047951122002633
Abstract: OBJECTIVE The Mesenchymal Stromal Cell Delivery through Cardiopulmonary Bypass in Pediatric Cardiac Surgery study is a prospective, open-label, single-centre, dose-escalation phase 1 trial assessing the safety/feasibility of delivering mesenchymal stromal cells to neonates/infants during cardiac… read more here.
Keywords: mesenchymal stromal; cardiopulmonary bypass; group; stromal cell ... See more keywords
Ex vivo biomechanical characterization of syringe-needle ejections for intracerebral cell delivery
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-27568-x
Abstract: Intracerebral implantation of cell suspensions is finding its clinical translation with encouraging results in patients with stroke. However, the survival of cells in the brain remains poor. Although the biological potential of neural stem cells… read more here.
Keywords: vivo biomechanical; syringe needle; cell; cell delivery ... See more keywords
Quantifying the limits of CAR T-cell delivery in mice and men
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2020.1013
Abstract: CAR (Chimeric Antigen Receptor) T cells have demonstrated clinical success for the treatment of multiple lymphomas and leukaemias, but not for various solid tumours, despite promising data from murine models. Lower effective CAR T-cell delivery… read more here.
Keywords: car cell; delivery; cell delivery; mice ... See more keywords
Polymeric microcarriers for minimally-invasive cell delivery
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1076179
Abstract: Tissue engineering (TE) aims at restoring tissue defects by applying the three-dimensional (3D) biomimetic pre-formed scaffolds to restore, maintain, and enhance tissue growth. Broadly speaking, this approach has created a potential impact in anticipating organ-building,… read more here.
Keywords: cell; polymeric microcarriers; delivery; cell delivery ... See more keywords
Mn-Based Methacrylated Gellan Gum Hydrogels for MRI-Guided Cell Delivery and Imaging
Sign Up to like & getrecommendations! Published in 2023 at "Bioengineering"
DOI: 10.3390/bioengineering10040427
Abstract: This work aims to engineer a new stable injectable Mn-based methacrylated gellan gum (Mn/GG-MA) hydrogel for real-time monitored cell delivery into the central nervous system. To enable the hydrogel visualization under Magnetic Resonance Imaging (MRI),… read more here.
Keywords: cell; gellan gum; methacrylated gellan; based methacrylated ... See more keywords