Hematopoietic (stem) cell development—how divergent are the roads taken?
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12879
Abstract: This article corrects: Hematopoietic (stem) cell development—how divergent are the roads taken? Volume 590, Issue 22, 3975–3986. Article first published online: 1 September 2016. DOI of original article: https://doi.org/10. 1002/1873-3468.12372. Funding from European Research Council… read more here.
Keywords: roads taken; cell development; stem cell; development divergent ... See more keywords
N6‐ Methyladenosine defines a new checkpoint in γδ T cell development
Sign Up to like & getrecommendations! Published in 2023 at "BioEssays"
DOI: 10.1002/bies.202300002
Abstract: T cells, which are derived from hematopoietic stem cells (HSCs), are the most important components of adaptive immune system. Based on the expression of αβ and γδ receptors, T cells are mainly divided into αβ… read more here.
Keywords: cell development; development; m6a modification; checkpoint cell ... See more keywords
Interferon regulatory factor-7 is required for hair cell development during zebrafish embryogenesis.
Sign Up to like & getrecommendations! Published in 2021 at "Developmental neurobiology"
DOI: 10.1002/dneu.22860
Abstract: Interferon regulatory factor-7 (IRF7) is an essential regulator of both innate and adaptive immunity. It is also expressed in the otic vesicle of zebrafish embryos. However, any role for irf7 in hair cell development was… read more here.
Keywords: hair cell; cell development; hair; gene ... See more keywords
mTORC2 regulates multiple aspects of NKT‐cell development and function
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Immunology"
DOI: 10.1002/eji.201646343
Abstract: Invariant NKT (iNKT) cells bridge innate and adaptive immunity by rapidly secreting cytokines and lysing targets following TCR recognition of lipid antigens. Based on their ability to secrete IFN‐γ, IL‐4 and IL‐17A, iNKT‐cells are classified… read more here.
Keywords: inkt; cell development; inkt cell; function ... See more keywords
BOB.1/OBF.1 is required during B‐cell ontogeny for B‐cell differentiation and germinal center function
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Immunology"
DOI: 10.1002/eji.202149333
Abstract: BOB.1/OBF.1 is a lymphocyte‐specific transcriptional co‐activator of octamer‐dependent transcription. It regulates the expression of genes important for lymphocyte physiology together with the Oct‐1 and Oct‐2 transcription factors. So far, BOB.1/OBF.1 has been studied in conventional… read more here.
Keywords: bob obf; cell development; cell; germinal center ... See more keywords
Isoform-specific functions of Ras in T-cell development and differentiation.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202350430
Abstract: Ras GTPases, well-characterized for their role in oncogenesis, are the cells' molecular switches that signal to maintain immune homeostasis through cellular development, proliferation, differentiation, survival, and apoptosis. In the immune system, T-cells are the central… read more here.
Keywords: development differentiation; development; cell development; ras cell ... See more keywords
RBM24 is required for mouse hair cell development through regulating pre‐mRNA alternative splicing and mRNA stability
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.31003
Abstract: As the sensory receptor cells in vertebrate inner ear and lateral lines, hair cells are characterized by the hair bundle that consists of one tubulin‐based kinocilium and dozens of actin‐based stereocilia on the apical surface… read more here.
Keywords: hair; mrna stability; hair cell; cell development ... See more keywords
High-Fat Diet from Weaning until Early Adulthood Impairs T Cell Development in the Thymus.
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DOI: 10.1002/lipd.12193
Abstract: The growing prevalence of childhood obesity has become a serious health problem over the past few decades. Although the immune system is greatly affected by childhood obesity, whether obesity influences the T cell development in… read more here.
Keywords: cell development; obesity; development thymus; mice ... See more keywords
Conditional deletion of mTOR discloses its essential role in early B‐cell development
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23386
Abstract: Mechanistic target of rapamycin (mTOR) is a serine‐threonine kinase and central regulator of cell growth, differentiation, and survival. mTOR is commonly hyperactivated in a diverse number of cancers and critical roles for mTOR in regulating… read more here.
Keywords: early cell; cell development; cell; essential role ... See more keywords
Live Imaging of Schwann Cell Development in Zebrafish.
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DOI: 10.1007/978-1-4939-7649-2_27
Abstract: The optical transparency of zebrafish larvae enables live imaging. Here we describe the methodology for live imaging and detail how to mount larvae for live imaging of Schwann cell development. read more here.
Keywords: imaging schwann; cell development; schwann cell; live imaging ... See more keywords
Epidermal resident γδ T cell development and function in skin
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-020-03613-9
Abstract: Epidermal resident γδ T cells, or dendritic epidermal T cells (DETCs) in mice, are a unique and conserved population of γδ T cells enriched in the epidermis, where they serve as the regulators of immune… read more here.
Keywords: cell development; resident cell; function; epidermal resident ... See more keywords