Microtissue Geometry and Cell-Generated Forces Drive Patterning of Liver Progenitor Cell Differentiation in 3D.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202100223
Abstract: 3D microenvironments provide a unique opportunity to investigate the impact of intrinsic mechanical signaling on progenitor cell differentiation. Using a hydrogel-based microwell platform, arrays of 3D, multicellular microtissues in constrained geometries, including toroids and cylinders… read more here.
Keywords: progenitor cell; geometry; cell; cell differentiation ... See more keywords
Soft Pneumatic Device Designed to Mimic the Periosteal Environment for Regulating the Fate of Mesenchymal Stem Cells
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202403229
Abstract: Replicating the complex mechanical forces of muscle movement and fluid flow in in vitro cell culture systems is crucial for understanding cell differentiation and development. However, previous research focused on cell differentiation on static micro/nanotextures… read more here.
Keywords: differentiation; cell differentiation; pneumatic device; soft pneumatic ... See more keywords
Chiral Nanoparticles Force Neural Stem Cell Differentiation to Alleviate Alzheimer's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202475
Abstract: The differentiation of neural stem cells via nanomaterials has attracted attention and has become a potential tool. However, the chirality effect in neural stem cell differentiation has not been investigated. Here, this study shows that… read more here.
Keywords: differentiation; cell differentiation; neural stem; stem cell ... See more keywords
Melatonin promotes neuroblastoma cell differentiation by activating hyaluronan synthase 3‐induced mitophagy
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2389
Abstract: Neuroblastoma is the second most common pediatric malignancy and has a high rate of spontaneous remission. Uncovering the mechanisms underlying neuroblastoma cell differentiation is critical for therapeutic purposes. A neuroblastoma cell line (N2a) treated with… read more here.
Keywords: hyaluronan synthase; cell differentiation; differentiation; neuroblastoma cell ... See more keywords
Exosomes Derived From BMMSCs Promote B10 Cell Differentiation but Not IL‐10 Production
Sign Up to like & getrecommendations! Published in 2025 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.70083
Abstract: The role of IL‐10‐producing regulatory B cells in inflammatory diseases has recently gained substantial attention. Here, we evaluated the function of mouse bone marrow mesenchymal stem cell‐derived exosomes (BMMSC‐Exos) and their effect on B‐cell differentiation.… read more here.
Keywords: differentiation; cell differentiation; bmmsc exos; exosomes derived ... See more keywords
Citrulline enteral administration markedly reduces immunosuppressive extrafollicular plasma cell differentiation in a preclinical model of sepsis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202250154
Abstract: The sustained immunosuppression associated with severe sepsis favors an increased susceptibility to secondary infections and remains incompletely understood. Plasmablast and plasma cell subsets, whose primary function is to secrete antibodies, have emerged as important suppressive… read more here.
Keywords: sepsis; cell; administration; plasma cell ... See more keywords
Exosome miR‐6990‐5p from MMP14high Macrophage Promotes Fibrosis Through Th17 Cell Differentiation in Hypersensitivity Pneumonia
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Immunology"
DOI: 10.1002/eji.70048
Abstract: Th17 cells contribute to pulmonary fibrosis, but the mechanisms driving their differentiation remain unclear. Using single‐cell RNA sequencing (scRNA‐seq) and a decision tree model, we identify IL17A as a key marker in mice exposed to… read more here.
Keywords: cell differentiation; mir; mir 6990; th17 cell ... See more keywords
Organization of cortical microtubules in differentiated cells.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular physiology"
DOI: 10.1002/jcp.31011
Abstract: The microtubule cytoskeleton plays a critical role in a variety of cellular activities, and its structures and functions have been extensively studied. However, little is known about cell differentiation-related microtubule remodeling, its regulatory mechanisms, and… read more here.
Keywords: differentiated cells; cell differentiation; organization cortical; microtubule ... See more keywords
Proprotein convertase inhibition promotes ciliated cell differentiation – a potential mechanism for the inhibition of Notch1 signalling by decanoyl‐RVKR‐chloromethylketone
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2240
Abstract: Chronic repetitive rounds of injury and repair in the airway lead to airway remodelling, including ciliated cell loss and mucous cell hyperplasia. Airway remodelling is mediated by many growth and differentiation factors including Notch1, which… read more here.
Keywords: medicine; ciliated cell; cell differentiation; inhibition ... See more keywords
Monitoring and Modulation of Inducible Foxp3+ Regulatory T-Cell Differentiation in the Lymph Nodes Draining the Small Intestine and Colon.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6786-5_16
Abstract: The mucosa-draining lymphoid tissue favors differentiation of inducible Foxp3+ regulatory T cells. Adoptive transfer of T-cell receptor (TCR) transgenic (Tg) T cells is a powerful tool to study antigen-specific regulatory T-cell differentiation in lymphoid tissues… read more here.
Keywords: lymph nodes; cell differentiation; regulatory cell; foxp3 regulatory ... See more keywords
In situ cell differentiation monitoring of Catharanthus roseus suspension culture processes by NIR spectroscopy
Sign Up to like & getrecommendations! Published in 2019 at "Bioprocess and Biosystems Engineering"
DOI: 10.1007/s00449-019-02255-x
Abstract: Plant suspension culture is attracting interest as a promising platform to produce biological medicines due to the absence of virus, prions or DNA related to mammals during the production process. However, the heterogenic plant cell… read more here.
Keywords: cell differentiation; plant; nir spectroscopy; spectroscopy ... See more keywords