Memory B‐cell diversity: From early generation to tissue residency and reactivation
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Immunology"
DOI: 10.1002/eji.202250085
Abstract: Memory B cells (MBCs) have a crucial function in providing an enhanced response to repeated infections. Upon antigen encounter, MBC can either rapidly differentiate to antibody secreting cells or enter germinal centers (GC) to further… read more here.
Keywords: reactivation; cell diversity; generation; memory cell ... See more keywords
The Broad Spectrum of Human Natural Killer Cell Diversity.
Sign Up to like & getrecommendations! Published in 2017 at "Immunity"
DOI: 10.1016/j.immuni.2017.10.008
Abstract: Natural killer (NK) cells provide protection against infectious pathogens and cancer. For decades it has been appreciated that two major NK cell subsets (CD56bright and CD56dim) exist in humans and have distinct anatomical localization patterns,… read more here.
Keywords: cell diversity; cell; natural killer; spectrum human ... See more keywords
Global patterns of antigen receptor repertoire disruption across adaptive immune compartments in COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2201541119
Abstract: Significance While making virus-specific immune responses to SARS-CoV-2, residual B and T cell diversity are key to making responses to concurrent co-infections and/or cancers. We applied an antigen receptor–sequencing technology and provide a comprehensive description… read more here.
Keywords: cell; antigen receptor; cell diversity; repertoire ... See more keywords
Cell diversity and immune infiltration in parathyroid tumour microenvironment.
Sign Up to like & getrecommendations! Published in 2023 at "Endocrine-related cancer"
DOI: 10.1530/erc-22-0325
Abstract: Tumour microenvironment has been recognized as a crucial factor influencing disease progression. However, relevant features and function are insufficiently understood in parathyroid neoplasia. Single-cell RNA sequencing was performed to profile the transcriptome of 27,251 cells… read more here.
Keywords: tumour microenvironment; cell; microenvironment; immune infiltration ... See more keywords
CA1 pyramidal cell diversity is rooted in the time of neurogenesis
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.69270
Abstract: Cellular diversity supports the computational capacity and flexibility of cortical circuits. Accordingly, principal neurons at the CA1 output node of the murine hippocampus are increasingly recognized as a heterogeneous population. Their genes, molecular content, intrinsic… read more here.
Keywords: ca1 pyramidal; cell diversity; physiology; diversity ... See more keywords