Tumor cell dormancy
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Oncology"
DOI: 10.1016/j.molonc.2016.09.009
Abstract: Metastasis is the primary cause of death in cancer patients and current treatments fail to provide durable responses. Efforts to treat metastatic disease are hindered by the fact that metastatic cells often remain dormant for… read more here.
Keywords: cell dormancy; dormancy; metastasis; tumor cell ... See more keywords
PAX5 haploinsufficiency induce cancer cell dormancy in Raji cells
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DOI: 10.1016/j.yexcr.2018.02.010
Abstract: ABSTRACT PAX5 mutations have important role in leukemogenesis and leukemia relapse, cancer cell dormancy participates in cancer relapse, but there was no report about PAX5 mutation inducing cancer cell dormancy. we constructed the PAX5 deletion… read more here.
Keywords: raji; cell; cell dormancy; cancer cell ... See more keywords
Tumor cell dormancy as an adaptive cell stress response mechanism
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DOI: 10.12688/f1000research.12174.1
Abstract: Metastases are responsible for most cancer-related deaths. The kinetics of tumor relapse is highly heterogeneous, ranging from recurrences shortly after diagnosis to years or even decades after the initial treatment. This subclinical period is known… read more here.
Keywords: dormancy adaptive; cell dormancy; dormancy; tumor cell ... See more keywords
Cancer cell dormancy: mechanisms and implications of cancer recurrence and metastasis
Sign Up to like & getrecommendations! Published in 2017 at "OncoTargets and therapy"
DOI: 10.2147/ott.s140854
Abstract: More recently, disease metastasis and relapse in many cancer patients several years (even some decades) after surgical remission are regarded as tumor dormancy. However, the knowledge of this phenomenon is cripplingly limited. Substantial quantities of… read more here.
Keywords: cell dormancy; dormancy; metastasis; cancer cell ... See more keywords