Nano-mechanical mapping of interdependent cell and ECM mechanics by AFM force spectroscopy
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48566-7
Abstract: Extracellular matrix (ECM), as a dynamic component of the tissue, influences cell behavior and plays an important role in cell mechanics and tissue homeostasis. Reciprocally, this three-dimensional scaffold is dynamically, structurally and mechanically modified by… read more here.
Keywords: topography; microscopy; spectroscopy; cell ecm ... See more keywords
RBFOX2 is required for establishing RNA regulatory networks essential for heart development
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac055
Abstract: Abstract Human genetic studies identified a strong association between loss of function mutations in RBFOX2 and hypoplastic left heart syndrome (HLHS). There are currently no Rbfox2 mouse models that recapitulate HLHS. Therefore, it is still… read more here.
Keywords: heart development; rbfox2; cell ecm; heart ... See more keywords
Disorder to order transition in cell-ECM systems mediated by cell-cell collective interactions.
Sign Up to like & getrecommendations! Published in 2022 at "Acta biomaterialia"
DOI: 10.2139/ssrn.4068152
Abstract: Cells in functional tissues execute various collective activities to achieve diverse ordered processes including wound healing, organogenesis, and tumor formation. How a group of individually operating cells initiate such complex collective processes is still not… read more here.
Keywords: compaction; cell; cell ecm; disorder order ... See more keywords
Modifying the Tumour Microenvironment: Challenges and Future Perspectives for Anticancer Plasma Treatments
Sign Up to like & getrecommendations! Published in 2019 at "Cancers"
DOI: 10.3390/cancers11121920
Abstract: Tumours are complex systems formed by cellular (malignant, immune, and endothelial cells, fibroblasts) and acellular components (extracellular matrix (ECM) constituents and secreted factors). A close interplay between these factors, collectively called the tumour microenvironment, is… read more here.
Keywords: cell ecm; tumour microenvironment; cell cell; plasma ... See more keywords