In silico prediction of T-cell and B-cell epitopes of human papillomavirus type 16 L1 protein.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2128
Abstract: Human papillomavirus type 16 (HPV-16) is one of the most important cause of developing cervical cancer. Therefore, effective epitope-based vaccine design for HPV-16 would be of major medical benefit. The aim of our study was… read more here.
Keywords: papillomavirus type; cell; cell epitopes; human papillomavirus ... See more keywords
Prediction of Pan‐Specific B‐Cell Epitopes From Nucleocapsid Protein of Hantaviruses Causing Hantavirus Cardiopulmonary Syndrome
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25887
Abstract: Hantaviruses are emerging viral pathogens that causes hantavirus cardiopulmonary syndrome (HCPS) in the Americas, a severe, sometimes fatal, respiratory disease in humans with a case fatality rate of ≥50%. IgM and IgG‐based serological detection methods… read more here.
Keywords: pan specific; cell epitopes; hantavirus; cell ... See more keywords
In Silico Identification of the B-Cell and T-Cell Epitopes of the Antigenic Proteins of Staphylococcus aureus for Potential Vaccines.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1892-9_23
Abstract: Staphylococcus aureus is a leading cause of community-acquired, healthcare-associated, and hospital-acquired infections. S. aureus bacteremia is a common and serious infection with significant morbidity and mortality in older patients. The rise of antibiotic-resistant strains of… read more here.
Keywords: antigenic proteins; cell; cell epitopes; cell cell ... See more keywords
Identification of three linear B cell epitopes against non-structural protein 3ABC of FMDV using monoclonal antibodies
Sign Up to like & getrecommendations! Published in 2019 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-019-10081-0
Abstract: Foot-and-mouth disease virus (FMDV) has led to serious losses in the farming industry worldwide, particularly in cattle and swine. In developing countries, the control and eradication of FMD rely upon vaccination, in which the inactivated… read more here.
Keywords: cell epitopes; linear cell; monoclonal antibodies; three linear ... See more keywords
Discovery of B-cell epitopes for development of dengue vaccines and antibody therapeutics
Sign Up to like & getrecommendations! Published in 2022 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-021-00726-1
Abstract: Dengue is one of the most frequently transmitted viral infections globally which creates a serious burden to the healthcare system in many countries in the tropical and subtropical regions. To date, no vaccine has demonstrated… read more here.
Keywords: dengue; antibody; cell epitopes; dengue vaccines ... See more keywords
Discovery of T-cell Driven Subunit Vaccines from Zika Virus Genome: An Immunoinformatics Approach
Sign Up to like & getrecommendations! Published in 2017 at "Interdisciplinary Sciences, Computational Life Sciences"
DOI: 10.1007/s12539-017-0238-3
Abstract: The recent outbreaks of Zika virus and the absence of a specific therapy have necessitated to identify T-cell-stimulating antigenic peptides as potential subunit vaccine candidates. The translated ssRNA (+) genome of Zika virus was explored… read more here.
Keywords: cell epitopes; vaccines zika; zika virus; cell ... See more keywords
In silico identification and characterization of common epitope-based peptide vaccine for Nipah and Hendra viruses.
Sign Up to like & getrecommendations! Published in 2017 at "Asian Pacific journal of tropical medicine"
DOI: 10.1016/j.apjtm.2017.06.016
Abstract: OBJECTIVE To explore a common B- and T-cell epitope-based vaccine that can elicit an immune response against encephalitis causing genus Henipaviruses, Hendra virus (HeV) and Nipah virus (NiV). METHODS Membrane proteins F, G and M… read more here.
Keywords: cell epitopes; cell; hev niv; epitope based ... See more keywords
Vaccine potential of ESAT-6 protein fused with consensus CD4+ T-cell epitopes of PE/PPE proteins against highly pathogenic Mycobacterium tuberculosis strain HN878.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.06.017
Abstract: Pro-Glu/Pro-Pro-Glu (PE/PPE) family proteins in Mycobacterium tuberculosis (Mtb) are contributors to pathogenesis and immune evasion. These proteins have a unique structure in which the sequence is conserved. We investigated the vaccine potential of ESAT-6 fused… read more here.
Keywords: cell epitopes; consensus cd4; cd4 cell; cell ... See more keywords
In silico prediction of T- and B-cell epitopes in PmpD: First step towards to the design of a Chlamydia trachomatis vaccine
Sign Up to like & getrecommendations! Published in 2018 at "Biomedical Journal"
DOI: 10.1016/j.bj.2018.04.007
Abstract: Background Chlamydia trachomatis is the most common sexually transmitted bacterial infection globally. Currently, there are no vaccines available despite the efforts made to develop a protective one. Polymorphic membrane protein D (PmpD) is an attractive… read more here.
Keywords: cell epitopes; affinity; epitopes pmpd; chlamydia trachomatis ... See more keywords
Immunoinformatics prediction of potential B-cell and T-cell epitopes as effective vaccine candidates for eliciting immunogenic responses against Epstein–Barr virus
Sign Up to like & getrecommendations! Published in 2021 at "Biomedical Journal"
DOI: 10.1016/j.bj.2020.01.002
Abstract: Background The ongoing search for viable treatment options to curtail Epstein Barr Virus (EBV) pathogenicity has necessitated a paradigmatic shift towards the design of peptide-based vaccines. Potential B-cell and T-cell epitopes were predicted for nine… read more here.
Keywords: cell cell; epstein barr; cell epitopes; potential cell ... See more keywords
Rational design of low immunogenic anti CD25 recombinant immunotoxin for T cell malignancies by elimination of T cell epitopes in PE38.
Sign Up to like & getrecommendations! Published in 2017 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2017.01.003
Abstract: LMB-2, is a potent recombinant immunotoxin (RIT) that is composed of scFv antibody that targets CD25 (Tac) and a toxin fragment (PE38). It is used to treat T cell leukemias and lymphomas. To make LMB-2… read more here.
Keywords: recombinant immunotoxin; lmb 142; cell epitopes; point mutations ... See more keywords