Impaired B Cell Expression of the Inhibitory Fcγ Receptor IIB in Myasthenia Gravis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26507
Abstract: Myasthenia gravis (MG) is an autoimmune disease in which pathogenic immunoglobulin G antibodies bind to acetylcholine receptors (or to functionally related molecules at the neuromuscular junction). B cell expression of the inhibitory immunoglobulin G receptor, Fc‐gamma receptor… read more here.
Keywords: receptor iib; cell expression; expression; expression inhibitory ... See more keywords
Single cell expression analysis of primate-specific retroviruses-derived HPAT lincRNAs in viable human blastocysts identifies embryonic cells co-expressing genetic markers of multiple lineages
Sign Up to like & getrecommendations! Published in 2018 at "Heliyon"
DOI: 10.1016/j.heliyon.2018.e00667
Abstract: Chromosome instability and aneuploidies occur very frequently in human embryos, impairing proper embryogenesis and leading to cell cycle arrest, loss of cell viability, and developmental failures in 50–80% of cleavage-stage embryos. This high frequency of… read more here.
Keywords: single cell; embryonic cells; cells expressing; expression ... See more keywords
Data-driven comparison of multiple high-dimensional single-cell expression profiles.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of human genetics"
DOI: 10.1038/s10038-021-00989-9
Abstract: Comparing multiple single-cell expression datasets such as cytometry and scRNA-seq data between case and control donors provides information to elucidate the mechanisms of disease. We propose a completely data-driven computational biological method for this task.… read more here.
Keywords: single cell; driven comparison; data driven; cell expression ... See more keywords
Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-26471-9
Abstract: Type 1 diabetes is caused by autoreactive T cell-mediated β cell destruction. Even though co-inhibitory receptor programmed death-1 (PD-1) restrains autoimmunity, the expression and regulation of its cognate ligands on β cell remains unknown. Here,… read more here.
Keywords: programmed death; death ligand; expression; cell expression ... See more keywords
scPreGAN, a deep generative model for predicting the response of single-cell expression to perturbation
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac357
Abstract: MOTIVATION Rapid developments of single cell RNA sequencing technologies allow study of responses to external perturbations at individual cell level. However, in many cases, it is hard to collect the perturbed cells, such as knowing… read more here.
Keywords: cell; scpregan deep; cell expression; expression ... See more keywords
The Solanum tuberosum KST1 partial promoter as a tool for guard cell expression in multiple plant species
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erx159
Abstract: The KST1 partial promoter is expressed in guard cells immediately after guard mother cell division and drives constitutive guard cell expression in dicots and monocots, and under drought and ABA treatment. read more here.
Keywords: guard cell; partial promoter; kst1 partial; cell expression ... See more keywords
CancerSCEM: a database of single-cell expression map across various human cancers.
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic acids research"
DOI: 10.1093/nar/gkab905
Abstract: With the proliferating studies of human cancers by single-cell RNA sequencing technique (scRNA-seq), cellular heterogeneity, immune landscape and pathogenesis within diverse cancers have been uncovered successively. The exponential explosion of massive cancer scRNA-seq datasets in… read more here.
Keywords: single cell; human cancers; cell expression; cancer ... See more keywords
Clustering Single-Cell Expression Data Using Random Forest Graphs
Sign Up to like & getrecommendations! Published in 2017 at "IEEE Journal of Biomedical and Health Informatics"
DOI: 10.1109/jbhi.2016.2565561
Abstract: Complex tissues such as brain and bone marrow are made up of multiple cell types. As the study of biological tissue structure progresses, the role of cell-type-specific research becomes increasingly important. Novel sequencing technology such… read more here.
Keywords: single cell; cell; cell types; clustering single ... See more keywords
Hierarchical Cluster Analysis of Cytokeratins and Stem Cell Expression Profiles of Canine Cutaneous Epithelial Tumors
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary Pathology"
DOI: 10.1177/0300985818785680
Abstract: The diagnosis of cutaneous epithelial tumors (CETs) in dogs is based on predominant histological differentiation patterns. However, the expression of a broad panel of antigens has not been comprehensively examined with immunohistochemistry. The present study… read more here.
Keywords: cutaneous epithelial; stem cell; cell expression; epithelial tumors ... See more keywords
Innovations in the Insect Cell Expression System for Industrial Recombinant Vaccine Antigen Production
Sign Up to like & getrecommendations! Published in 2021 at "Vaccines"
DOI: 10.3390/vaccines9121504
Abstract: The insect cell expression system has previously been proposed as the preferred biosecurity strategy for production of any vaccine, particularly for future influenza pandemic vaccines. The development and regulatory risk for new vaccine candidates is… read more here.
Keywords: expression system; vaccine; production; cell expression ... See more keywords
Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.43882
Abstract: Besides cardiomyocytes (CM), the heart contains numerous interstitial cell types which play key roles in heart repair, regeneration and disease, including fibroblast, vascular and immune cells. However, a comprehensive understanding of this interactive cell community… read more here.
Keywords: cell expression; vascular immune; cell; single cell ... See more keywords