The Use of Microfluidic Platforms to Probe the Mechanism of Cancer Cell Extravasation.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901410
Abstract: Powerful experimental tools have contributed a wealth of novel insight into cancer etiology from the organ to the subcellular levels. However, these advances in understanding have outpaced improvements in clinical outcomes. One possible reason for… read more here.
Keywords: microfluidic platforms; use microfluidic; cell extravasation; cancer cell ... See more keywords
Docking of Meprin α to Heparan Sulphate Protects the Endothelium from Inflammatory Cell Extravasation.
Sign Up to like & getrecommendations! Published in 2018 at "Thrombosis and haemostasis"
DOI: 10.1055/s-0038-1670657
Abstract: Pulmonary arterial hypertension (PAH) is a rare disease characterized by increased pulmonary pressure and vascular remodelling as a consequence of smooth muscle cell proliferation, endothelial cell dysfunction and inflammatory infiltrates. Meprin α is a metalloproteinase… read more here.
Keywords: cell extravasation; meprin; cell; inflammatory cell ... See more keywords
Abstract B22: Role of monocytes in 3D microfluidic models of cancer cell extravasation
Sign Up to like & getrecommendations! Published in 2017 at "Cancer immunology research"
DOI: 10.1158/2326-6074.tumimm16-b22
Abstract: Intravital imaging can be performed in mice and has proven extremely useful in uncovering the role of immune cells in cancer metastasis, but requires specialized expertise and equipment. In the last decade, microfluidic models have… read more here.
Keywords: cell extravasation; extravasation; cancer cell; cancer ... See more keywords
Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurodegeneration"
DOI: 10.1186/s13024-018-0303-3
Abstract: BackgroundGlaucoma is characterized by the progressive dysfunction and loss of retinal ganglion cells. Recent work in animal models suggests that a critical neuroinflammatory event damages retinal ganglion cell axons in the optic nerve head during… read more here.
Keywords: monocyte like; cell extravasation; cell; glaucoma ... See more keywords
Macrophages Promote Tumor Cell Extravasation across an Endothelial Barrier through Thin Membranous Connections.
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15072092
Abstract: Macrophages are important players involved in the progression of breast cancer, including in seeding the metastatic niche. However, the mechanism by which macrophages in the lung parenchyma interact with tumor cells in the vasculature to… read more here.
Keywords: cell; tumor cells; tumor cell; tumor ... See more keywords