Cell fate‐inducing CARs orthogonally control multiple signaling pathways
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DOI: 10.1002/biot.202100463
Abstract: While chimeric antigen receptor (CAR) has been clinically applied in T cell‐mediated cancer therapy, CARs that combinatorially control general cell fates have yet to be practical. In this study, we aim to control multiple cell… read more here.
Keywords: cell fate; cell; fate inducing; control multiple ... See more keywords
Mesenchymal Stem Cell Fates in Murine Acute Liver Injury and Chronic Liver Fibrosis Induced by Carbon Tetrachloride
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DOI: 10.1124/dmd.122.000958
Abstract: Mesenchymal stem cells (MSCs) therapy has shown potential benefits in multiple diseases. However, their clinic performance is not as satisfactory as expected. This study aimed to provide an alternative explanation by comparing MSCs’ fates in… read more here.
Keywords: cell; liver; hmscs; liver injury ... See more keywords
Bicaudal-C Post-transcriptional regulator of cell fates and functions
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DOI: 10.3389/fcell.2022.981696
Abstract: Bicaudal-C (Bicc1) is an evolutionarily conserved RNA binding protein that functions in a regulatory capacity in a variety of contexts. It was originally identified as a genetic locus in Drosophila that when disrupted resulted in… read more here.
Keywords: bicaudal post; regulator; cell fates; post transcriptional ... See more keywords