Long noncoding RNA THRIL promotes foam cell formation and inflammation in macrophages
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DOI: 10.1002/cbin.11934
Abstract: Tumor necrosis factor‐α (TNF‐α) and heterogenous nuclear ribonucleoprotein L (hnRNPL)‐related immunoregulatory lincRNA (THRIL) is a long noncoding RNA (lncRNA) involved in various inflammatory diseases. However, its role in atherosclerosis is not known. In this study,… read more here.
Keywords: inflammation; thril; foam cell; rna ... See more keywords
Mechanisms of foam cell formation in atherosclerosis
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DOI: 10.1007/s00109-017-1575-8
Abstract: Low-density lipoprotein (LDL) and cholesterol homeostasis in the peripheral blood is maintained by specialized cells, such as macrophages. Macrophages express a variety of scavenger receptors (SR) that interact with lipoproteins, including SR-A1, CD36, and lectin-like… read more here.
Keywords: foam cell; cell formation; formation atherosclerosis; cholesterol ... See more keywords
Clematichinenoside AR Alleviates Foam Cell Formation and the Inflammatory Response in Ox-LDL-Induced RAW264.7 Cells by Activating Autophagy
Sign Up to like & getrecommendations! Published in 2020 at "Inflammation"
DOI: 10.1007/s10753-020-01375-x
Abstract: Foam cell formation and inflammation in macrophages contribute to the development of atherosclerosis (AS). Clematichinenoside AR (AR) is a major active ingredient extracted from the traditional Chinese herb Clematis chinensis and has potent pharmacological effects… read more here.
Keywords: cell formation; foam cell; formation; induced raw264 ... See more keywords
Evaluation of gene expression and protein structural modeling involved in persister cell formation in Salmonella Typhimurium
Sign Up to like & getrecommendations! Published in 2020 at "Brazilian Journal of Microbiology"
DOI: 10.1007/s42770-020-00388-w
Abstract: Persisters are phenotypic variants of the bacterial population that survive against lethal doses of bactericidal antibiotics.These phenotypes are created in numerous bacterial species, including those of clinical significance, such as Salmonella Typhimurium. Since persister cells… read more here.
Keywords: cell formation; persister cells; persister; formation ... See more keywords
Silencing LAIR‐1 in human THP‐1 macrophage increases foam cell formation by modulating PPAR&ggr; and M2 polarization
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.08.028
Abstract: Graphical abstract Figure. No caption available. HighlightsLAIR‐1 was down‐regulated in macrophage with the stimulation of ox‐LDL.Silencing expression of LAIR‐1 in human macrophages increased cholesterol uptake.LAIR‐1 activated phosphorylation of SHP‐1 and CREB to induce PPAR&ggr;, thus… read more here.
Keywords: cell formation; lair; foam cell; ppar ggr ... See more keywords
Oxygen-free cell formation process obtaining LiF protected electrodes for improved stability in lithium-oxygen batteries
Sign Up to like & getrecommendations! Published in 2019 at "Energy Storage Materials"
DOI: 10.1016/j.ensm.2019.02.032
Abstract: Abstract The unsatisfactory stabilities of carbon-based cathodes and lithium anodes are the major hurdles limiting the development of Li-air (O2) batteries. Herein, we propose an extremely simple cell formation process for non-aqueous Li-O2 batteries, by… read more here.
Keywords: cell formation; oxygen batteries; lithium oxygen; process ... See more keywords
PPARα/γ signaling pathways are involved in Chlamydia pneumoniae-induced foam cell formation via upregulation of SR-A1 and ACAT1 and downregulation of ABCA1/G1.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2021.105284
Abstract: Chlamydia pneumoniae (Cpn) has been reported to be involved in the pathogenesis of early atherosclerosis by inducing macrophage-derived foam cell formation in the presence of low-density lipoprotein (LDL). However, the biochemical mechanisms underlying Cpn-induced foam… read more here.
Keywords: ppar; foam cell; cell formation;
Thioredoxin-interacting protein is essential for memory T cell formation via the regulation of the redox metabolism.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2218345120
Abstract: CD4+ memory T cells are central to long-lasting protective immunity and are involved in shaping the pathophysiology of chronic inflammation. While metabolic reprogramming is critical for the generation of memory T cells, the mechanisms controlling… read more here.
Keywords: memory; metabolism; cell formation; memory cell ... See more keywords
NP-completeness of cell formation problem with grouping efficacy objective
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DOI: 10.1080/00207543.2019.1668072
Abstract: In the current paper we provide a proof of NP-completeness for the Cell Formation Problem (CFP) with the fractional grouping efficacy objective function. First the CFP with a linear objective function is considered. Following the… read more here.
Keywords: cell formation; efficacy objective; completeness cell; grouping efficacy ... See more keywords
Insights into the molecular determinants involved in Mycobacterium tuberculosis persistence and their therapeutic implications.
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DOI: 10.1080/21505594.2021.1990660
Abstract: The establishment of persistent infections and the reactivation of persistent bacteria to active bacilli are the two hurdles in effective tuberculosis treatment. Mycobacterium tuberculosis, an etiologic tuberculosis agent, adapts to numerous antibiotics and resists the… read more here.
Keywords: cell formation; tuberculosis; persistence; persister cell ... See more keywords
Combination of Antibiotics-Nisin Reduces the Formation of Persister Cell in Listeria monocytogenes.
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DOI: 10.1089/mdr.2020.0019
Abstract: Persister cells are a subpopulation of bacteria with the ability of survival when exposed to lethal doses of antibiotics, and are responsible for antibiotic therapy failure and infection recurrences. In this study, we investigated persister… read more here.
Keywords: combination; persister; cell formation; persister cell ... See more keywords