Impact of the age-related protein aggregate lipofuscin on β-cell functionality
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.04.247
Abstract: The formation of cross-linked protein aggregates such as lipofuscin is a typical hallmark of cellular aging and especially affects long-living and postmitotic cells such as neurons and skeletal muscle cells. Lipofuscin can neither be degraded… read more here.
Keywords: age; impact; cell functionality; lipofuscin ... See more keywords
Impact of Manufacturing Procedures on CAR T Cell Functionality
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.876339
Abstract: The field of chimeric antigen receptor (CAR) modified T cell therapy has rapidly expanded in the past few decades. As of today, there are six CAR T cell products that have been approved by the… read more here.
Keywords: cd19 car; car; cell functionality; car cell ... See more keywords
Enhancement of SARS-CoV-2 N Antigen-Specific T Cell Functionality by Modulating the Autophagy-Mediated Signal Pathway in Mice
Sign Up to like & getrecommendations! Published in 2023 at "Viruses"
DOI: 10.3390/v15061316
Abstract: The frequent SARS-CoV-2 variants have caused a continual challenge, weakening the effectiveness of current vaccines, and thus it is of great importance to induce robust and conserved T cellular immunity for developing the next-generation vaccine… read more here.
Keywords: cell; signal pathway; specific cell; cell functionality ... See more keywords