Articles with "cell fusion" as a keyword



Enhancement of polyethylene glycol‐cell fusion efficiency by novel application of transient pressure using a jet injector

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Published in 2023 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13557

Abstract: Cell–cell fusion involves the fusion of somatic cells into a single hybrid cell. It is not only a physiological process but also an important cell engineering technology which can be applied to various fields, such… read more here.

Keywords: cell fusion; cell; fusion; peg method ... See more keywords

Cellular reprogramming by single‐cell fusion with mouse embryonic stem cells in pig

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Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.29244

Abstract: Fusion of differentiated somatic cells with pluripotent stem cells can be used for cellular reprogramming, but the efficiency to obtain hybrid cells is extremely low. Here, we explored a novel cell fusion system, termed single‐cell… read more here.

Keywords: fusion; single cell; stem cells; cell fusion ... See more keywords

A Cell-Cell Fusion Assay to Assess Arenavirus Envelope Glycoprotein Membrane-Fusion Activity.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-6981-4_10

Abstract: For many viruses that enter their target cells through pH-dependent fusion of the viral and endosomal membranes, cell-cell fusion assays can provide an experimental platform for investigating the structure-function relationships that promote envelope glycoprotein membrane-fusion… read more here.

Keywords: cell cell; cell fusion; envelope glycoprotein; fusion ... See more keywords
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Mechanistic insights of host cell fusion of SARS-CoV-1 and SARS-CoV-2 from atomic resolution structure and membrane dynamics

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Published in 2020 at "Biophysical Chemistry"

DOI: 10.1016/j.bpc.2020.106438

Abstract: Abstract The emerging and re-emerging viral diseases are continuous threats to the wellbeing of human life. Previous outbreaks of Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS had evidenced potential threats of… read more here.

Keywords: fusion; sars cov; host cell; cell fusion ... See more keywords
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Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion.

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Published in 2021 at "Developmental cell"

DOI: 10.1016/j.devcel.2021.01.016

Abstract: Cell-cell fusion is a frequent and essential event during development, and its dysregulation causes diseases ranging from infertility to muscle weakness. Fusing cells need to repeatedly remodel their plasma membrane through orchestrated formation and disassembly… read more here.

Keywords: fusion; actin cytoskeleton; cell fusion; ubiquitin dependent ... See more keywords

Promoting Cell Fusion by Polyvalent DNA Ligands.

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Published in 2022 at "Nano letters"

DOI: 10.1021/acs.nanolett.2c00216

Abstract: Artificially induced in vitro cell fusion is one essential technique that has been extensively used for biological studies. Nevertheless, there is a lack of robust and efficient method to produce fused cells efficiently. Herein, we… read more here.

Keywords: polyvalent dna; cell fusion; dna ligands; cell ... See more keywords

The microprotein Minion controls cell fusion and muscle formation

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Published in 2017 at "Nature Communications"

DOI: 10.1038/ncomms15664

Abstract: Although recent evidence has pointed to the existence of small open reading frame (smORF)-encoded microproteins in mammals, their function remains to be determined. Skeletal muscle development requires fusion of mononuclear progenitors to form multinucleated myotubes,… read more here.

Keywords: cell fusion; muscle; minion; microprotein minion ... See more keywords

Cell surface crowding is a tunable energetic barrier to cell-cell fusion

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Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-62330-8

Abstract: Cell-cell fusion is fundamental to processes such as muscle formation and viral infection. An essential step in fusion is close membrane apposition, but cell membranes are crowded with proteins, glycoproteins, and glycolipids, which must be… read more here.

Keywords: cell cell; fusion; cell; cell fusion ... See more keywords

Scoring rings in the cell fusion-induced premature chromosome condensation (PCC) assay for high dose radiation exposure estimation after gamma-ray exposure

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Published in 2019 at "International Journal of Radiation Biology"

DOI: 10.1080/09553002.2019.1625465

Abstract: Abstract Purpose: This study aimed to construct a calibration curve for high-dose exposure using cell fusion-induced premature chromosome condensation (PCC). Some of the associated practicalities and methodological details were also investigated. Materials and methods: Peripheral… read more here.

Keywords: cell fusion; high dose; exposure; fusion induced ... See more keywords

Macrophage-cancer cell fusion is mediated by phosphatidylserine-CD36 receptor interaction and induced by ionizing radiation

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Published in 2019 at "Annals of Oncology"

DOI: 10.1093/annonc/mdz238.069

Abstract: Abstract Background Cell fusion (CF) is a normal biological process that plays major role in mammalian development and differentiation. Through CF, somatic cells acquire nuclear reprogramming and epigenetic modifications to form pluripotent hybrid cells, which… read more here.

Keywords: cell fusion; cd36; macrophage; cancer ... See more keywords

Identification of regions required for allelic specificity at the cell wall remodeling allorecognition checkpoint in Neurospora crassa

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Published in 2025 at "Genetics"

DOI: 10.1093/genetics/iyaf062

Abstract: Allorecognition is the ability of organisms/cells to differentiate self from non-self. In the fungus Neurospora crassa, allorecognition systems serve as checkpoints to restrict germling/hyphal fusion between genetically incompatible strains. The cell wall remodeling (cwr) checkpoint… read more here.

Keywords: cwr; allorecognition; cell wall; cell ... See more keywords