The β-Cell Genomic Landscape in T1D: Implications for Disease Pathogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Current Diabetes Reports"
DOI: 10.1007/s11892-020-01370-4
Abstract: Purpose of Review Type 1 diabetes (T1D) develops as a consequence of a combination of genetic predisposition and environmental factors. Combined, these events trigger an autoimmune disease that results in progressive loss of pancreatic β… read more here.
Keywords: t1d; cell genomic; t1d risk; pathogenesis ... See more keywords
A CRISPR/molecular beacon hybrid system for live-cell genomic imaging
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky304
Abstract: Abstract The clustered regularly interspersed short palindromic repeat (CRISPR) gene-editing system has been repurposed for live-cell genomic imaging, but existing approaches rely on fluorescent protein reporters, making sensitive and continuous imaging difficult. Here, we present… read more here.
Keywords: system; live cell; molecular beacon; genomic imaging ... See more keywords