Northern pig‐tailed macaques (Macaca leonina) maintain superior CD4+ T‐cell homeostasis during SIVmac239 infection
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Immunology"
DOI: 10.1002/eji.201747284
Abstract: Gradual depletion of CD4+ T cells is a typical characteristic of pathogenic SIV infection. Intriguingly, we find a spontaneous CD4+ T-cell homeostasis in northern pig-tailed macaques (Macaca leonina) during SIVmac239 infection. read more here.
Keywords: northern pig; infection; cell homeostasis; cd4 cell ... See more keywords
Claspin functions in cell homeostasis-A link to cancer?
Sign Up to like & getrecommendations! Published in 2017 at "DNA repair"
DOI: 10.1016/j.dnarep.2017.09.002
Abstract: Cancer remains one of the leading causes of mortality worldwide. Most cancers present high degrees of genomic instability. DNA damage and replication checkpoints function as barriers to halt cell cycle progression until damage is resolved,… read more here.
Keywords: claspin functions; cell homeostasis; claspin; cancer ... See more keywords
Altered naive CD4+ T cell homeostasis in myasthenia gravis and thymoma patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2019.01.005
Abstract: In Myasthenia Gravis (MG) thymic pathologies are often present and thymectomy is used as treatment. By flow cytometry we elucidated alterations of naïve CD4+ T cell homeostasis in MG patients and patients with thymoma. MG… read more here.
Keywords: cell homeostasis; cd4 cell; cd4; thymoma patients ... See more keywords
Nitrate, NO and ROS Signaling in Stem Cell Homeostasis.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in plant science"
DOI: 10.1016/j.tplants.2018.09.010
Abstract: Shoot and root growth is facilitated by stem cells in the shoot and root apical meristems (SAM and RAM). Recent reports have demonstrated a close link between nitrogen nutrition, nitric oxide (NO), and reactive oxygen… read more here.
Keywords: stem cell; cell homeostasis; signaling stem; stem ... See more keywords
The mitochondrial nucleoside diphosphate kinase (NDPK-D/NME4), a moonlighting protein for cell homeostasis
Sign Up to like & getrecommendations! Published in 2018 at "Laboratory Investigation"
DOI: 10.1038/s41374-017-0004-5
Abstract: Mitochondrial nucleoside diphosphate kinase (NDPK-D; synonyms: NME4, NM23-H4) represents the major mitochondrial NDP kinase. The homohexameric complex emerged as a protein with multiple functions in bioenergetics and phospholipid signaling. It occurs at different but precise… read more here.
Keywords: kinase ndpk; nucleoside diphosphate; diphosphate kinase; kinase ... See more keywords
Intestinal fibroblastic reticular cell niches control innate lymphoid cell homeostasis and function.
Sign Up to like & getrecommendations! Published in 2022 at "Nature communications"
DOI: 10.1038/s41467-022-29734-2
Abstract: Innate lymphoid cells (ILCs) govern immune cell homeostasis in the intestine and protect the host against microbial pathogens. Various cell-intrinsic pathways have been identified that determine ILC development and differentiation. However, the cellular components that… read more here.
Keywords: homeostasis; fibroblastic reticular; cell homeostasis; innate lymphoid ... See more keywords
Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4+ T cell homeostasis
Sign Up to like & getrecommendations! Published in 2018 at "Nature immunology"
DOI: 10.1038/s41590-018-0103-5
Abstract: Nuclear pore complexes (NPCs) are channels connecting the nucleus with the cytoplasm. We report that loss of the tissue-specific NPC component Nup210 causes a severe deficit of naïve CD4+ T cells. Nup210-deficient CD4+ T lymphocytes… read more here.
Keywords: cell homeostasis; tcr signaling; cd4 cell; cell ... See more keywords
Arp2/3 complex controls T cell homeostasis by maintaining surface TCR levels via regulating TCR+ endosome trafficking
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-08357-4
Abstract: T cell receptor (TCR) signaling is important for T cell homeostasis and function. However, how surface TCR levels are regulated and its biological significance on T cells remains largely unknown. Here, we show that the… read more here.
Keywords: arp2 complex; tcr levels; cell homeostasis; surface tcr ... See more keywords
Immune homeostasis in health and disease
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DOI: 10.1111/imcb.12043
Abstract: The immune system is one of the most dynamic in our bodies. The mechanisms that maintain immune homeostasis must contend with the constant churn of cell proliferation and death across a myriad of lineages at… read more here.
Keywords: homeostasis; cell homeostasis; immune homeostasis; health disease ... See more keywords
Spatiotemporal diversity and regulation of glycosaminoglycans in cell homeostasis and human disease
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Physiology - Cell Physiology"
DOI: 10.1152/ajpcell.00085.2022
Abstract: Glycosaminoglycans (GAGs) are long, linear polysaccharides that are ubiquitously expressed on the cell surface and in the extracellular matrix of all animal cells. These complex carbohydrates play important roles in many cellular processes and have… read more here.
Keywords: disease; spatiotemporal diversity; physiology; cell homeostasis ... See more keywords
NAD+-Consuming Enzymes in Stem Cell Homeostasis
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DOI: 10.1155/2023/4985726
Abstract: Nicotinamide adenine dinucleotide (NAD+) is a coenzyme used in redox reactions, energy metabolism, and mitochondrial biogenesis. NAD+ is also required as a cofactor by nonredox NAD+-dependent enzymes. Hundreds of enzymes that consume NAD+ have been… read more here.
Keywords: cell homeostasis; consuming enzymes; nad consuming; stem cell ... See more keywords