Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma
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DOI: 10.1016/j.bbi.2017.01.022
Abstract: Glioblastoma (GBM) is the most common malignant brain tumor in adults with a median survival of 14.6months. A contributing factor to GBM aggressiveness is the intratumoral expression of the potently immunosuppressive enzyme, indoleamine 2,3 dioxygenase… read more here.
Keywords: cell ido1; non tumor; tumor cell; cell ... See more keywords