Rapid Screen for Antiviral T‐Cell Immunity with Nanowire Electrochemical Biosensors
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202109661
Abstract: The ability to rapidly assess and monitor patient immune responses is critical for clinical diagnostics, vaccine design, and fundamental investigations into the presence or generation of protective immunity against infectious diseases. Recently, findings on the… read more here.
Keywords: cell; screen antiviral; immunity; rapid screen ... See more keywords
Progress on chicken T cell immunity to viruses
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-019-03117-1
Abstract: Avian virus infection remains one of the most important threats to the poultry industry. Pathogens such as avian influenza virus (AIV), avian infectious bronchitis virus (IBV), and infectious bursal disease virus (IBDV) are normally controlled… read more here.
Keywords: immunity viruses; chicken cell; virus; cell immunity ... See more keywords
Dyrsregulation of T cell immunity in adopted human adolescents
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2017.07.126
Abstract: Seminal discoveries in our field demonstrated early rearing conditions play an important role in guiding the normal development of the immune system. Violation of the inherent expectation for parenting derails not only behavioral and brain… read more here.
Keywords: immunity; adopted human; cell immunity; dyrsregulation cell ... See more keywords
Discovery of BAY-405: An Azaindole-Based MAP4K1 Inhibitor for the Enhancement of T-Cell Immunity against Cancer
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.4c01325
Abstract: Mitogen-activated protein kinase kinase kinase kinase 1 (MAP4K1) is a serine/threonine kinase that acts as an immune checkpoint downstream of T-cell receptor stimulation. MAP4K1 activity is enhanced by prostaglandin E2 (PGE2) and transforming growth factor… read more here.
Keywords: cell immunity; bay 405; cell; kinase ... See more keywords
Engineering Dendritic-Cell-Based Vaccines and PD-1 Blockade in Self-Assembled Peptide Nanofibrous Hydrogel to Amplify Antitumor T-Cell Immunity.
Sign Up to like & getrecommendations! Published in 2018 at "Nano letters"
DOI: 10.1021/acs.nanolett.8b01406
Abstract: Dendritic cells (DCs) are increasingly used in cancer vaccines due to their ability to regulate T-cell immunity. Major limitations associated with the present DC adoptive transfer immunotherapy are low cell viability and transient duration of… read more here.
Keywords: cell immunity; antitumor; vaccine; cell ... See more keywords
Microenvironmental influences on T cell immunity in cancer and inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-021-00833-2
Abstract: T cell metabolism is dynamic and highly regulated. While the intrinsic metabolic programs of T cell subsets are integral to their distinct differentiation and functional patterns, the ability of cells to acquire nutrients and cope… read more here.
Keywords: cancer; immunity; influences cell; cell immunity ... See more keywords
Increased NK cell immunity in a transgenic mouse model of NKp46 overexpression
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12998-w
Abstract: Natural Killer (NK) cells employ activating receptors like the Natural Cytotoxicity Receptors (NCRs: NKp30, NKp44 and NKp46), of which only NKp46 has a mouse orthologue (Ncr1), to eliminate abnormal cells. NKp46/Ncr1 is considered a selective… read more here.
Keywords: overexpression; cell immunity; increased cell; transgenic mouse ... See more keywords
Ectopic germinal centers in the nasal turbinates contribute to B cell immunity to intranasal viral infection and vaccination
Sign Up to like & getrecommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2421724122
Abstract: Significance Respiratory viral diseases are a significant public health threat. The first line of immune defense is within the upper respiratory tract (URT). Despite this fundamental role, critical aspects of humoral immunity within the URT… read more here.
Keywords: immunity; cell immunity; ectopic germinal; centers nasal ... See more keywords
Exploit T cell Immunity for Rapid, Safe and Effective COVID-19 Vaccines
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2020.1825946
Abstract: The world needs a vaccine urgently to recover from the COVID-19 pandemic. In the race to a vaccine, several companies and funders are pursuing the most obvious approach, which is to develop antibody-focused vaccines based… read more here.
Keywords: immunity; cell immunity; sars cov; vaccine ... See more keywords
The potential role of CMC1 as an immunometabolic checkpoint in T cell immunity
Sign Up to like & getrecommendations! Published in 2024 at "Oncoimmunology"
DOI: 10.1080/2162402x.2024.2344905
Abstract: ABSTRACT T cell immunity is critical for human defensive immune response. Exploring the key molecules during the process provides new targets for T cell-based immunotherapies. CMC1 is a mitochondrial electron transport chain (ETC) complex IV… read more here.
Keywords: cell; cell immunity; role cmc1; cmc1 ... See more keywords
The Function of T Cell Immunity in Lymphedema: A Comprehensive Review.
Sign Up to like & getrecommendations! Published in 2023 at "Lymphatic research and biology"
DOI: 10.1089/lrb.2023.0002
Abstract: Lymphedema is a debilitating disease characterized by extremity edema, fibroadipose deposition, impaired lymphangiogenesis, and dysfunctional lymphatics, often with lymphatic injury secondary to the treatment of malignancies. Emerging evidence has shown that immune dysfunction regulated by… read more here.
Keywords: cell; function cell; review; immunity lymphedema ... See more keywords