Enhanced Natural Killer Cell Immunotherapy by Rationally Assembling Fc Fragments of Antibodies onto Tumor Membranes.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201804395
Abstract: Recent advances in cancer immunotherapy have exploited the efficient potential of natural killer (NK) cells to kill tumor cells through antibody-dependent cell-mediated cytotoxicity (ADCC). However, this therapeutic strategy is seriously limited by tumor antigen heterogeneity… read more here.
Keywords: fragments antibodies; cell immunotherapy; natural killer; tumor ... See more keywords
Nanomedicine for T-Cell Mediated Immunotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202301770
Abstract: T cell immunotherapy offers outstanding advantages in the treatment of various diseases, and with the selection of appropriate targets, efficient disease treatment can be achieved. T cell immunotherapy has made great progress, but clinical results… read more here.
Keywords: cell; immunotherapy; mediated immunotherapy; cell immunotherapy ... See more keywords
Genome-Editing Technologies in Adoptive T Cell Immunotherapy for Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Current Hematologic Malignancy Reports"
DOI: 10.1007/s11899-017-0417-7
Abstract: Purpose of ReviewIn this review, we discuss the most recent developments in gene-editing technology and discuss their application to adoptive T cell immunotherapy.Recent FindingsEngineered T cell therapies targeting cancer antigens have demonstrated significant efficacy in… read more here.
Keywords: cell immunotherapy; adoptive cell; editing technologies; cancer ... See more keywords
Gearing up T-cell immunotherapy in cervical cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Current problems in cancer"
DOI: 10.1016/j.currproblcancer.2018.04.001
Abstract: The World Health Organization estimates more than 270,000 deaths annually by cervical cancer. Present vaccines are prophylactic in nature which cannot treat huge bulk of cervical cancer patients worldwide. Available therapies like radiotherapy, chemotherapy, or… read more here.
Keywords: cancer gearing; cell immunotherapy; cervical cancer; cancer ... See more keywords
T cell immunotherapy for cardiac fibrosis: mRNA starts the CAR.
Sign Up to like & getrecommendations! Published in 2022 at "Cell stem cell"
DOI: 10.1016/j.stem.2022.02.002
Abstract: Fibrosis, or chronic fibroblast activation and extracellular matrix deposition, underlies most cardiovascular diseases and remains challenging to target therapeutically. Reported in Science by Rurik et al., modified mRNA technology can reprogram endogenous T cells into fibroblast-ablating CAR-Ts… read more here.
Keywords: cell immunotherapy; immunotherapy cardiac; cell; fibrosis ... See more keywords
The natural killer cell immunotherapy platform: An overview of the landscape of clinical trials in liquid and solid tumors.
Sign Up to like & getrecommendations! Published in 2023 at "Seminars in hematology"
DOI: 10.1053/j.seminhematol.2023.02.002
Abstract: The translation of natural killer (NK) cells to the treatment of malignant disease has made significant progress in the last few decades. With a variety of available sources and improvements in both in vitro and… read more here.
Keywords: platform; clinical trials; natural killer; cell immunotherapy ... See more keywords
Recent advances in T‐cell immunotherapy for haematological malignancies
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Haematology"
DOI: 10.1111/bjh.14470
Abstract: In vitro discoveries have paved the way for bench‐to‐bedside translation in adoptive T cell immunotherapy, resulting in remarkable clinical responses in a variety of haematological malignancies. Adoptively transferred T cells genetically modified to express CD19… read more here.
Keywords: cell immunotherapy; advances cell; haematological malignancies; immunotherapy haematological ... See more keywords
Phase III randomized trial of autologous cytokine-induced killer cell immunotherapy for newly diagnosed glioblastoma in korea
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.12273
Abstract: Purpose Adoptive cell immunotherapy involves an ex vivo expansion of autologous cytokine-induced killer (CIK) cells before their reinfusion into the host. We evaluated the efficacy and safety of CIK cell immunotherapy with radiotherapy-temozolomide (TMZ) for… read more here.
Keywords: cell immunotherapy; newly diagnosed; immunotherapy; group ... See more keywords
Enhancement of dendritic cell immunotherapy by recalling antigens for hepatocellular carcinoma in mice.
Sign Up to like & getrecommendations! Published in 2022 at "Immunotherapy"
DOI: 10.2217/imt-2021-0254
Abstract: Background: The therapeutic efficacy of dendritic cell (DC)-immunotherapy for large hepatoma in mice is unsatisfactory. Materials & methods: DC-based immunotherapy was used to treat Hepa1-6 tumors measuring 6 ± 1 mm in diameter, enhanced by boosting tumor antigens. Results:… read more here.
Keywords: tumor; cell immunotherapy; dendritic cell; mice ... See more keywords
T Cell Defects: New Insights Into the Primary Resistance Factor to CD19/CD22 Cocktail CAR T-Cell Immunotherapy in Diffuse Large B-Cell Lymphoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.873789
Abstract: Despite impressive progress, a significant portion of patients still experience primary or secondary resistance to chimeric antigen receptor (CAR) T-cell immunotherapy for relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL). The mechanism of primary resistance involves… read more here.
Keywords: primary resistance; cell; car; cell immunotherapy ... See more keywords
T cell immunotherapy for cervical cancer: challenges and opportunities
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1105265
Abstract: Cancer cellular immunotherapy has made inspiring therapeutic effects in clinical practices, which brings new hope for the cure of cervical cancer. CD8+T cells are the effective cytotoxic effector cells against cancer in antitumor immunity, and… read more here.
Keywords: cervical cancer; immunotherapy cervical; cell immunotherapy; cancer challenges ... See more keywords